Anti-MMP25抗体- C-terminal (ab70881)

概述

  • 产品名称Anti-MMP25抗体- C-terminal
    参阅全部 MMP25 一抗
  • 描述
    兔多克隆抗体to MMP25 - C-terminal
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide from the C terminal region of human MMP25 conjugated to KLH

  • 阳性对照
    • Mouse liver tissue and HL60 cell lysates.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab70881 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 63 kDa (predicted molecular weight: 63 kDa).

靶标

  • 功能May activate progelatinase A.
  • 组织特异性Expressed predominantly in leukocytes, lung and spleen. Expressed also in colon carcinoma, astrocytoma and glioblastomas.
  • 序列相似性Belongs to the peptidase M10A family.
    Contains 4 hemopexin repeats.
  • 结构域The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • 翻译后修饰The precursor is cleaved by a furin endopeptidase.
  • 细胞定位Cell membrane. Secreted, extracellular space, extracellular matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Leukolysin antibody
    • matrix metallopeptidase 25 antibody
    • matrix metallopeptidase like 1 antibody
    • matrix metalloproteinase 20 antibody
    • Matrix Metalloproteinase 25 antibody
    • Matrix metalloproteinase 25 precursor antibody
    • Matrix metalloproteinase-25 antibody
    • Membrane type 6 Matrix Metalloproteinase antibody
    • Membrane type Matrix Metalloproteinase 6 antibody
    • Membrane-type matrix metalloproteinase 6 antibody
    • Membrane-type-6 matrix metalloproteinase antibody
    • MMP 25 antibody
    • MMP-25 antibody
    • MMP20 antibody
    • MMP20A antibody
    • MMP25 antibody
    • MMP25_HUMAN antibody
    • MMPL1 antibody
    • MT-MMP 6 antibody
    • MT6-MMP antibody
    • MT6MMP antibody
    • MTMMP6 antibody
    see all

Anti-MMP25 antibody - C-terminal 图像

  • All lanes : Anti-MMP25 antibody - C-terminal (ab70881) at 1/100 dilution

    Lane 1 : Mouse liver tissue lysate
    Lane 2 : HL60 cell lysate

    Lysates/proteins at 12.5 µg per lane.


    Predicted band size : 63 kDa
    Observed band size : 63 kDa

Anti-MMP25 antibody - C-terminal (ab70881)参考文献

ab70881 has not yet been referenced specifically in any publications.

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