概述

  • 产品名称Anti-MMP23抗体
    参阅全部 MMP23 一抗
  • 描述
    兔多克隆抗体to MMP23
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide derived from the C terminus of human MMP23 protein.

  • 阳性对照
    • Paraffin embedded Human placenta tissue.

性能

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应用

Our Abpromise guarantee covers the use of ab74215 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/25 for 10 min at RT.
    Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Protease. May regulate the surface expression of some potassum channels by retaining them in the endoplasmic reticulum.
    • 组织特异性Predominantly expressed in ovary, testis and prostate.
    • 序列相似性Belongs to the peptidase M10A family.
      Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    • 结构域The toxin-like domain associates with, and blocks several potassium channels in the nanomolar to low micromolar range. The relative affinity is Kv1.6 > Kv1.3 > Kv1.1 = Kv3.2 > Kv1.4.
    • 翻译后修饰N-glycosylated.
      Proteolytic cleavage might yield an active form.
    • 细胞定位Endoplasmic reticulum membrane. Membrane. A secreted form produced by proteolytic cleavage may also exist.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Femalysin antibody
      • Matrix metallopeptidase 21 antibody
      • Matrix metallopeptidase 23A (pseudogene) antibody
      • Matrix metallopeptidase 23A antibody
      • Matrix metallopeptidase 23B antibody
      • Matrix metalloproteinase 22 antibody
      • Matrix metalloproteinase 23 antibody
      • Matrix metalloproteinase 23B antibody
      • Matrix metalloproteinase in the female reproductive tract antibody
      • Matrix metalloproteinase-21 antibody
      • Matrix metalloproteinase-22 antibody
      • Matrix metalloproteinase-23 antibody
      • MIFR antibody
      • MIFR-1 antibody
      • MIFR1 antibody
      • MMP 23 antibody
      • MMP-21 antibody
      • MMP-22 antibody
      • MMP-23 antibody
      • MMP21 antibody
      • MMP22 antibody
      • MMP23_HUMAN antibody
      • MMP23A antibody
      • MMP23B antibody
      • soluble form antibody
      see all

    Anti-MMP23 antibody 图像

    • ab74215 at 1/25 dilution staining MMP23 in human placenta by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.

    Anti-MMP23 antibody (ab74215)参考文献

    ab74215 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"