概述

  • 产品名称Anti-MMP23抗体
    参阅全部 MMP23 一抗
  • 描述
    兔多克隆抗体to MMP23
  • 特异性MMP23 (Cleaved-Tyr79) antibody detects endogenous levels of fragment of activated MMP23 resulting from cleavage adjacent to Tyr79.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Pig, Chimpanzee, Zebrafish
  • 免疫原

    Synthetic peptide (Human)

  • 阳性对照
    • Extracts from 293 cells, treated with etoposide (25uM, 1hour).

性能

应用

Our Abpromise guarantee covers the use of ab72799 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 44 kDa.
ELISA 1/5000.

靶标

  • 功能Protease. May regulate the surface expression of some potassum channels by retaining them in the endoplasmic reticulum.
  • 组织特异性Predominantly expressed in ovary, testis and prostate.
  • 序列相似性Belongs to the peptidase M10A family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
  • 结构域The toxin-like domain associates with, and blocks several potassium channels in the nanomolar to low micromolar range. The relative affinity is Kv1.6 > Kv1.3 > Kv1.1 = Kv3.2 > Kv1.4.
  • 翻译后修饰N-glycosylated.
    Proteolytic cleavage might yield an active form.
  • 细胞定位Endoplasmic reticulum membrane. Membrane. A secreted form produced by proteolytic cleavage may also exist.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Femalysin antibody
    • Matrix metallopeptidase 21 antibody
    • Matrix metallopeptidase 23A (pseudogene) antibody
    • Matrix metallopeptidase 23A antibody
    • Matrix metallopeptidase 23B antibody
    • Matrix metalloproteinase 22 antibody
    • Matrix metalloproteinase 23 antibody
    • Matrix metalloproteinase 23B antibody
    • Matrix metalloproteinase in the female reproductive tract antibody
    • Matrix metalloproteinase-21 antibody
    • Matrix metalloproteinase-22 antibody
    • Matrix metalloproteinase-23 antibody
    • MIFR antibody
    • MIFR-1 antibody
    • MIFR1 antibody
    • MMP 23 antibody
    • MMP-21 antibody
    • MMP-22 antibody
    • MMP-23 antibody
    • MMP21 antibody
    • MMP22 antibody
    • MMP23_HUMAN antibody
    • MMP23A antibody
    • MMP23B antibody
    • soluble form antibody
    see all

Anti-MMP23 antibody 图像

  • All lanes : Anti-MMP23 antibody (ab72799) at 1/1000 dilution

    Lane 1 : 293 cells
    Lane 2 : 293 cells with MMP23 (cleaved Tyr79) blocking peptide at 5 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 44 kDa

Anti-MMP23 antibody (ab72799)参考文献

ab72799 has not yet been referenced specifically in any publications.

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