概述

  • 产品名称Anti-MMP23抗体
    参阅全部 MMP23 一抗
  • 描述
    兔多克隆抗体to MMP23
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide derived from human MMP23.

  • 阳性对照
    • SKOV3 cell extracts.

性能

应用

Our Abpromise guarantee covers the use of ab53148 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 44 kDa (predicted molecular weight: 44 kDa).
ELISA 1/10000.

靶标

  • 功能Protease. May regulate the surface expression of some potassum channels by retaining them in the endoplasmic reticulum.
  • 组织特异性Predominantly expressed in ovary, testis and prostate.
  • 序列相似性Belongs to the peptidase M10A family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
  • 结构域The toxin-like domain associates with, and blocks several potassium channels in the nanomolar to low micromolar range. The relative affinity is Kv1.6 > Kv1.3 > Kv1.1 = Kv3.2 > Kv1.4.
  • 翻译后修饰N-glycosylated.
    Proteolytic cleavage might yield an active form.
  • 细胞定位Endoplasmic reticulum membrane. Membrane. A secreted form produced by proteolytic cleavage may also exist.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Femalysin antibody
    • Matrix metallopeptidase 21 antibody
    • Matrix metallopeptidase 23A (pseudogene) antibody
    • Matrix metallopeptidase 23A antibody
    • Matrix metallopeptidase 23B antibody
    • Matrix metalloproteinase 22 antibody
    • Matrix metalloproteinase 23 antibody
    • Matrix metalloproteinase 23B antibody
    • Matrix metalloproteinase in the female reproductive tract antibody
    • Matrix metalloproteinase-21 antibody
    • Matrix metalloproteinase-22 antibody
    • Matrix metalloproteinase-23 antibody
    • MIFR antibody
    • MIFR-1 antibody
    • MIFR1 antibody
    • MMP 23 antibody
    • MMP-21 antibody
    • MMP-22 antibody
    • MMP-23 antibody
    • MMP21 antibody
    • MMP22 antibody
    • MMP23_HUMAN antibody
    • MMP23A antibody
    • MMP23B antibody
    • soluble form antibody
    see all

Anti-MMP23 antibody 图像

  • All lanes : Anti-MMP23 antibody (ab53148) at 1/500 dilution

    Lane 1 : Extracts from SKOV3 cells
    Lane 2 : Extracts from SKOV3 cells with immunising peptide


    Predicted band size : 44 kDa
    Observed band size : 44 kDa

Anti-MMP23 antibody (ab53148)参考文献

This product has been referenced in:
  • Miller JP  et al. Matrix Metalloproteinases Are Modifiers of Huntingtin Proteolysis and Toxicity in Huntington's Disease. Neuron 67:199-212 (2010). WB ; Human . Read more (PubMed: 20670829) »

See 1 Publication for this product

Product Wall

The MMP23 antibody ab53148 was raised against a peptide within amino acids 360-390 which is a range located at the C terminus of the protein, accession O75900, http://www.uniprot.org/uniprot/O75900.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"