参阅全部 MMP22 一抗
Mouse, Rat, Guinea pig, Cow, Cat, Dog
Synthetic peptide corresponding to a region within internal sequence amino acids 324-373 (KILHKKGKVY WYKDQEPLEF SYPGYLALGE AHLSIIANAV NEGTYTCVVR) of Human MMP22 (NP_008914).
- Human fetal liver lysate.
- 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
- 存储溶液Preservative: None
Constituents: 2% Sucrose, PBS
Concentration information loading...
- 纯度Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 1 µg/ml. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
- 功能Protease. May regulate the surface expression of some potassum channels by retaining them in the endoplasmic reticulum.
- 组织特异性Predominantly expressed in ovary, testis and prostate.
- 序列相似性Belongs to the peptidase M10A family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
- 结构域The toxin-like domain associates with, and blocks several potassium channels in the nanomolar to low micromolar range. The relative affinity is Kv1.6 > Kv1.3 > Kv1.1 = Kv3.2 > Kv1.4.
Proteolytic cleavage might yield an active form.
- 细胞定位Endoplasmic reticulum membrane. Membrane. A secreted form produced by proteolytic cleavage may also exist.
Information by UniProt
- Femalysin antibody
- Matrix metallopeptidase 21 antibody
- matrix metallopeptidase 23B antibody
Anti-MMP22 antibody (ab87066)参考文献
has not yet been referenced specifically in any publications.
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