Anti-MMP15抗体, prediluted (ab15476)

概述

  • 产品名称Anti-MMP15抗体, prediluted
    参阅全部 MMP15 一抗
  • 描述
    兔多克隆抗体to MMP15, prediluted
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    A synthetic peptide from the catalytic domain of mouse MMP15 protein.

  • 阳性对照
    • Placenta.

性能

应用

Our Abpromise guarantee covers the use of ab15476 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: Ready diluted for 10 min at RT. No special pretreatment is required for the immunohistochemical staining of formalin/paraffin tissues.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A.
    • 组织特异性Appeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, kidney, lung, heart and skeletal muscle.
    • 序列相似性Belongs to the peptidase M10A family.
      Contains 4 hemopexin-like domains.
    • 结构域The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
    • 翻译后修饰The precursor is cleaved by a furin endopeptidase.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AI503551 antibody
      • Matrix metallopeptidase 15 membrane inserted antibody
      • Matrix metalloproteinase 15 antibody
      • Matrix metalloproteinase-15 antibody
      • Membrane type 2 matrix metalloproteinase antibody
      • Membrane type matrix metalloproteinase 2 antibody
      • Membrane-type matrix metalloproteinase 2 antibody
      • Membrane-type-2 matrix metalloproteinase antibody
      • MMP 15 antibody
      • MMP-15 antibody
      • MMP15 antibody
      • MMP15_HUMAN antibody
      • MT MMP 2 antibody
      • MT-MMP 2 antibody
      • MT2 MMP antibody
      • MT2-MMP antibody
      • MT2MMP antibody
      • MTMMP 2 antibody
      • MTMMP2 antibody
      • SMCP 2 antibody
      • SMCP-2 antibody
      • SMCP2 antibody
      see all

    Anti-MMP15 antibody, prediluted 图像

    • ab15476 staining MMP15 in human placenta by Immunocytochemistry (FFPE-sections).

    Anti-MMP15 antibody, prediluted (ab15476)参考文献

    ab15476 has not yet been referenced specifically in any publications.

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