Anti-MMP15抗体[MM0028-5D11] (ab56308)

概述

  • 产品名称Anti-MMP15抗体[MM0028-5D11]
    参阅全部 MMP15 一抗
  • 描述
    小鼠单克隆抗体[MM0028-5D11] to MMP15
  • 特异性ab56308 recognizes human MMP15 in western blot without cross reactivity with human MMP14/16. Reactivity with MMP15 in other species has not been tested.
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human recombinant MMP15

性能

应用

Our Abpromise guarantee covers the use of ab56308 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/200.
WB Use at an assay dependent concentration. Predicted molecular weight: 76 kDa.

靶标

  • 功能Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A.
  • 组织特异性Appeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, kidney, lung, heart and skeletal muscle.
  • 序列相似性Belongs to the peptidase M10A family.
    Contains 4 hemopexin-like domains.
  • 结构域The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • 翻译后修饰The precursor is cleaved by a furin endopeptidase.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AI503551 antibody
    • Matrix metallopeptidase 15 membrane inserted antibody
    • Matrix metalloproteinase 15 antibody
    • Matrix metalloproteinase-15 antibody
    • Membrane type 2 matrix metalloproteinase antibody
    • Membrane type matrix metalloproteinase 2 antibody
    • Membrane-type matrix metalloproteinase 2 antibody
    • Membrane-type-2 matrix metalloproteinase antibody
    • MMP 15 antibody
    • MMP-15 antibody
    • MMP15 antibody
    • MMP15_HUMAN antibody
    • MT MMP 2 antibody
    • MT-MMP 2 antibody
    • MT2 MMP antibody
    • MT2-MMP antibody
    • MT2MMP antibody
    • MTMMP 2 antibody
    • MTMMP2 antibody
    • SMCP 2 antibody
    • SMCP-2 antibody
    • SMCP2 antibody
    see all

Anti-MMP15 antibody [MM0028-5D11] 图像

  • ab56308 at 1/200 dilution, staining MMP15 in human placental tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections).

Anti-MMP15 antibody [MM0028-5D11] (ab56308)参考文献

ab56308 has not yet been referenced specifically in any publications.

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Thank you for your enquiry. We do not have set expiration dates for our products. Most antibodies are stable and can last for anywhere from a few months to several years if stored properly, so we strongly recommend that you follow the storage instr...

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Thank you for contacting us. I was informed that it was tested to pick up the extracellular domain of the recombinant protein. Unfortunately, we do not have the detailed epitope information available. We aim to provide as much information...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"