概述

  • 产品名称Anti-MMP11抗体
    参阅全部 MMP11 一抗
  • 描述
    兔多克隆抗体to MMP11
  • 经测试应用适用于: WB, IHC-P, ICC/IF, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide conjugated to KLH, derived from internal sequence amino acids of Human MMP11.

  • 阳性对照
    • Human placenta and spleen tissues; A549 cell lysate; A549 cells.

性能

应用

Our Abpromise guarantee covers the use of ab119284 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 55 kDa.
IHC-P Use a concentration of 10 µg/ml.
ICC/IF 1/100 - 1/500.
ELISA 1/20000.

靶标

  • 功能May play an important role in the progression of epithelial malignancies.
  • 组织特异性Specifically expressed in stromal cells of breast carcinomas.
  • 序列相似性Belongs to the peptidase M10A family.
    Contains 4 hemopexin-like domains.
  • 结构域The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • 翻译后修饰The precursor is cleaved by a furin endopeptidase.
  • 细胞定位Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Matrix Metalloproteinase 11 antibody
    • Matrix metalloproteinase-11 antibody
    • MMP-11 antibody
    • Mmp11 antibody
    • MMP11_HUMAN antibody
    • SL 3 antibody
    • SL-3 antibody
    • SL3 antibody
    • ST3 antibody
    • STMY3 antibody
    • Stromelysin 3 antibody
    • Stromelysin III antibody
    • Stromelysin-3 antibody
    see all

Anti-MMP11 antibody 图像

  • ab119284, at 10 µg/ml, staining MMP11 in Formalin-fixed, Paraffin-embedded Human placenta tissue by Immunohistochemistry.
  • ab119284, at 10 µg/ml, staining MMP11 in Formalin-fixed, Paraffin-embedded Human spleen tissue by Immunohistochemistry.
  • All lanes : Anti-MMP11 antibody (ab119284) at 1/500 dilution

    Lane 1 : A549 cell lysate
    Lane 2 : A549 cell lysate with synthesized peptide


    Predicted band size : 55 kDa
  • ab119284, at 1/100, staining MMP11 in A549 cells by Immunofluorescence. The image on the right shows cells treated with synthesised peptide.

Anti-MMP11 antibody (ab119284)参考文献

ab119284 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab119284.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"