产品名称 Anti-MMAA抗体 参阅全部 MMAA 一抗
WB, IHC-P more details
Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 63-92 of Human MMAA.
Mouse liver tissue lysate; human skeletal muscle tissue
存放说明 Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
存储溶液 Preservative: 0.09% Sodium Azide
Concentration information loading...
纯度 Immunogen affinity purified
纯化说明 ab103459 is purified through a protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 47 kDa.
1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
功能 Probable GTPase. May function as chaperone. May be involved in the transport of cobalamin (Cbl) into mitochondria for the final steps of adenosylcobalamin (AdoCbl) synthesis.
组织特异性 Widely expressed. Highest expression is observed in liver and skeletal muscle.
通路 Cofactor biosynthesis; adenosylcobalamin biosynthesis.
疾病相关 Defects in MMAA are the cause of methylmalonic aciduria type cblA (MMAA) [MIM:251100]; also known as methylmalonic aciduria type A or vitamin B12-responsive methylmalonicaciduria of cblA complementation type. MMAA is a disorder of methylmalonate and cobalamin metabolism due to defective synthesis of adenosylcobalamin. Inheritance is autosomal recessive.
序列相似性 Belongs to the ArgK family.
Information by UniProt
Methylmalonic aciduria (cobalamin deficiency) cblA type antibody
Methylmalonic aciduria (cobalamin deficiency) type A antibody
Anti-MMAA antibody 图像
Western blot - MMAA antibody (ab103459)
Anti-MMAA antibody (ab103459) at 1/100 dilution + Mouse liver tissue lysate at 35 µg Predicted band size : 47 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - MMAA antibody (ab103459)
ab103459, at 1/50 dilution, staining MMAA in formalin-fixed, paraffin-embedded human skeletal muscle tissue by Immunohistochemistry using a peroxidase conjugated secondary antibody and DAB staining.
Anti-MMAA antibody (ab103459)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"