概述

  • 产品名称Anti-MLYCD抗体
    参阅全部 MLYCD 一抗
  • 描述
    小鼠多克隆抗体to MLYCD
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length human MLYCD protein (NP_036345.2).

  • 阳性对照
    • MLYCD transfected 293T lysate.

应用

Our Abpromise guarantee covers the use of ab69675 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 55 kDa.

靶标

  • 功能Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids.
  • 通路Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from malonyl-CoA: step 1/1.
  • 疾病相关Malonyl-CoA decarboxylase deficiency (MLYCD deficiency) [MIM:248360]: Autosomal recessive disease characterized by abdominal pain, chronic constipation, episodic vomiting, metabolic acidosis and malonic aciduria. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • 细胞定位Mitochondrion. Cytoplasm. Peroxisome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DCMC_HUMAN antibody
    • hMCD antibody
    • Malonyl CoA decarboxylase antibody
    • Malonyl CoA decarboxylase mitochondrial antibody
    • Malonyl coenzyme A decarboxylase antibody
    • Malonyl-CoA decarboxylase antibody
    • MCD antibody
    • MGC59795 antibody
    • mitochondrial antibody
    • Mlycd antibody
    see all

Anti-MLYCD antibody (ab69675)参考文献

ab69675 has not yet been referenced specifically in any publications.

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