概述

  • 产品名称Anti-MLLT1抗体
    参阅全部 MLLT1 一抗
  • 描述
    兔多克隆抗体to MLLT1
  • 特异性This antibody recognizes MLLT1
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    A region within synthetic peptide: SEDEASFKSE SAQSSPSNSS SSSDSSSDSD FEPSQNHSQG PLRSMVEDLQ, corresponding to internal sequence amino acids 361-410 of Human MLLT1

  • 阳性对照
    • Raji cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab49052 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/12500.
WB Use a concentration of 1.4 µg/ml. Detects a band of approximately 58 kDa (predicted molecular weight: 62 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Capable of activating transcription from synthetic reporter genes in both lymphoid and myeloid cells.
  • 疾病相关Note=A chromosomal aberration involving MLLT1 is associated with acute leukemias. Translocation t(11;19)(q23;p13.3) with MLL/HRX. The result is a rogue activator protein.
  • 序列相似性Contains 1 YEATS domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ENL antibody
    • ENL_HUMAN antibody
    • LTG19 antibody
    • MLLT1 antibody
    • Myeloid/lymphoid or mixed lineage leukemia trithorax (Drosophila) antibody
    • Protein ENL antibody
    • YEATS domain containing protein 1 antibody
    • YEATS domain-containing protein 1 antibody
    • YEATS1 antibody
    see all

Anti-MLLT1 antibody 图像

  • Anti-MLLT1 antibody (ab49052) at 1.4 µg/ml + Raji cell lysate at 10 µg with 5% skimmed milk in PBS.

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 62 kDa
    Observed band size : 58 kDa (why is the actual band size different from the predicted?)

Anti-MLLT1 antibody (ab49052)参考文献

This product has been referenced in:
  • Dey SS  et al. Mutual Information Analysis Reveals Coevolving Residues in Tat That Compensate for Two Distinct Functions in HIV-1 Gene Expression. J Biol Chem 287:7945-55 (2012). WB ; Human . Read more (PubMed: 22253435) »

See 1 Publication for this product

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