概述

  • 产品名称
  • 描述
    兔多克隆抗体to MLK2
  • 经测试应用
    适用于: ELISA, WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide from the C-terminal region of human MLK2, conjugated to KLH.

  • 阳性对照
    • MLK2 transfected COS7 cell lysate, human breast carcinoma tissue

性能

应用

Our Abpromise guarantee covers the use of ab70859 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
IHC-P
  • 应用说明
    ELISA: 1/1000.
    IHC-P: 1/50 - 1/1000.
    WB: 1/100 - 1/5000. Detects a band of approximately 120 kDa (predicted molecular weight: 103 kDa). Detection of endogenous proteins has not yet been validated.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Activates the JUN N-terminal pathway.
    • 组织特异性
      Expressed in brain and skeletal muscle.
    • 序列相似性
      Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
      Contains 1 protein kinase domain.
      Contains 1 SH3 domain.
    • 翻译后修饰
      Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation.
    • Information by UniProt
    • 数据库链接
    • 别名
      • M3K10_HUMAN antibody
      • MAP3K 10 antibody
      • Map3k10 antibody
      • MEKK10 antibody
      • Mitogen activated protein kinase kinase kinase 10 antibody
      • Mitogen-activated protein kinase kinase kinase 10 antibody
      • Mixed lineage kinase 2 antibody
      • MKN28 derived nonreceptor type serine/threonine kinase antibody
      • MKN28 kinase antibody
      • MLK 2 antibody
      • MST antibody
      • Protein kinase MST antibody
      see all

    图片

    • Anti-MLK2 antibody (ab70859) at 1/100 dilution + transfected COS7 cell lysate at 12.5 µg

      Predicted band size : 103 kDa
      Observed band size : 120 kDa (why is the actual band size different from the predicted?)
    • Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with 1/50 ab70859. A peroxidase-conjugated secondary antibody was then used, followed by DAB staining.

    文献

    ab70859 has not yet been referenced specifically in any publications.

    客户评价及客户问答

    There are currently no Customer reviews or Questions for ab70859.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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