概述

  • 产品名称
  • 描述
    兔多克隆抗体to Miz1
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 84-225 of Human Miz1.

  • 阳性对照
    • Human bronchus tissue

性能

应用

Our Abpromise guarantee covers the use of ab121232 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Use buffer at pH6 for antigen retrieval.

靶标

  • 功能
    May function as a housekeeping DNA-binding protein that regulates the expression of specific genes. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Also has potent growth arrest activity, probably through inhibition of cell cycle progression. Required for early embryonic development during gastrulation.
  • 序列相似性
    Belongs to the krueppel C2H2-type zinc-finger protein family.
    Contains 1 BTB (POZ) domain.
    Contains 13 C2H2-type zinc fingers.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Miz-1 antibody
    • Myc-interacting zinc finger protein 1 antibody
    • Myc-interacting zinc finger protein antibody
    • ZBT17 antibody
    • ZBT17_HUMAN antibody
    • Zbtb17 antibody
    • Zinc finger and BTB domain containing protein 17 antibody
    • Zinc finger and BTB domain-containing protein 17 antibody
    • Zinc finger protein 151 antibody
    • Zinc finger protein 60 antibody
    • ZNF151 antibody
    • ZNF60 antibody
    see all

图片

  • ab121232, at 1/250 dilution, staining Miz1 in Human bronchus tissue by Immunohistochemistry using formalin-fixed, paraffin-embedded tissue.

    Note: shows strong nuclear and moderate cytoplasmic and membranous positivity in respiratory epithelial cells.

文献

ab121232 has not yet been referenced specifically in any publications.

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