Anti-Mitofusin 1抗体(ab111271)

概述

  • 产品名称Anti-Mitofusin 1抗体
    参阅全部 Mitofusin 1 一抗
  • 描述
    山羊多克隆抗体to Mitofusin 1
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide from Human Mitofusin 1.

  • 阳性对照
    • Human Adrenal and Human Uterus tissues.

性能

应用

Our Abpromise guarantee covers the use of ab111271 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.
  • 组织特异性Ubiquitous. Expressed at slightly higher level in kidney and heart. Isoform 2 may be overexpressed in some tumors, such as lung cancers.
  • 序列相似性Belongs to the mitofusin family.
  • 翻译后修饰Ubiquitinated by MARCH5.
  • 细胞定位Cytoplasm and Mitochondrion outer membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Fzo homolog antibody
    • Hfzo1 antibody
    • Hfzo2 antibody
    • MFN 1 antibody
    • Mfn1 antibody
    • MFN1_HUMAN antibody
    • Mitochondrial transmembrane GTPase Fzo 1 antibody
    • Mitochondrial transmembrane GTPase FZO 2 antibody
    • Mitochondrial transmembrane GTPase FZO1B antibody
    • Mitofusin 1 antibody
    • Mitofusin-1 antibody
    • Mitofusin1 antibody
    • MS996 antibody
    • Putative transmembrane GTPase antibody
    • Transmembrane GTPase MFN1 antibody
    see all

Anti-Mitofusin 1 antibody 图像

  • ab111271, at 3.75µg/ml, staining Mitofusin 1 in formalin-fixed, paraffin-embedded Human Adrenal tissue by Immunohistochemistry.
  • ab111271, at 3.75µg/ml, staining Mitofusin 1 in formalin-fixed, paraffin-embedded Human Uterus tissue by Immunohistochemistry.

Anti-Mitofusin 1 antibody (ab111271)参考文献

ab111271 has not yet been referenced specifically in any publications.

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