RabMAb

Anti-Mitochondrial Ferritin抗体[EPR1797] (ab124889)

概述

  • 产品名称Anti-Mitochondrial Ferritin抗体[EPR1797]
    参阅全部 Mitochondrial Ferritin 一抗
  • 描述
    兔单克隆抗体[EPR1797] to Mitochondrial Ferritin
  • 经测试应用适用于: WBmore details
    不适用于: IHC-P or IP
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to Human Mitochondrial Ferritin aa 200-300 (C terminal).
    Database link: Q8N4E7

  • 阳性对照
    • Human Testis lysate.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

应用

Our Abpromise guarantee covers the use of ab124889 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 22 kDa (predicted molecular weight: 28 kDa).
  • 应用说明Is unsuitable for IHC-P or IP.
  • 靶标

    • 功能Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
    • 组织特异性Detected in testis and erythroleukemia. Expression is very low or not detectable in brain, colon, heart, kidney, liver, lung, muscle, placental, spleen and small intestine.
    • 序列相似性Belongs to the ferritin family.
      Contains 1 ferritin-like diiron domain.
    • 细胞定位Mitochondrion.
    • Information by UniProt
    • 数据库链接
    • 别名
      • FerH antibody
      • Ferritin antibody
      • Ferritin H subunit antibody
      • Ferritin, mitochondrial antibody
      • Fth 3 antibody
      • Fth3 antibody
      • FTMT antibody
      • FTMT_HUMAN antibody
      • mitochondrial antibody
      • Mitochondrial ferritin antibody
      • MTF antibody
      • OTTHUMP00000159158 antibody
      see all

    Anti-Mitochondrial Ferritin antibody [EPR1797] 图像

    • Anti-Mitochondrial Ferritin antibody [EPR1797] (ab124889) at 1/1000 dilution + Human Testis lysate at 10 µg

      Secondary
      Goat anti-Rabbit HRP at 1/2000 dilution

      Predicted band size : 28 kDa
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    Anti-Mitochondrial Ferritin antibody [EPR1797] (ab124889)参考文献

    This product has been referenced in:
    • Shi ZH  et al. Mitochondrial ferritin, a new target for inhibiting neuronal tumor cell proliferation. Cell Mol Life Sci N/A:N/A (2014). WB . Read more (PubMed: 25213357) »

    See 1 Publication for this product

    Product Wall

    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application Western blot
    Sample Human Cell lysate - whole cell (HepG2)
    Loading amount 50 µg
    Specification HepG2
    Gel Running Conditions Reduced Denaturing (4-12%)
    Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
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    提交于 Jul 02 2012

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"