概述

  • 产品名称
    Misoprostol
  • 描述
    Cytoprotective PGE2 analog
  • 别名
    • SC-29333
  • 生物学描述
    Cytoprotective PGE2 analog with activity mediated by EP2, EP3, and EP4 receptors (Ki values are 250, 67 and 67 nM, respectively).
  • 纯度
    > 98%

性能

  • 化学名称
    (11α,13E)-(±)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid methyl ester
  • 分子量
    382.54
  • 化学结构
    Chemical Structure
  • 分子式
    C22H38O5
  • CAS编号
    59122-46-2
  • 存放说明
    Store at -20°C (desiccating conditions).
  • 溶解度概述
    Supplied in methyl acetate (10 mg/ml)
  • 处理

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    CCCCC(C)(O)C/C=C/[C@H]1C(O)CC(=O)C1CCCCCCC(=O)OC
  • 来源

    Synthetic

  • 研究领域

文献

This product has been referenced in:
  • Tamiji J & Crawford DA Misoprostol elevates intracellular calcium in Neuro-2a cells via protein kinase A. Biochem Biophys Res Commun 399:565-70 (2010). Read more (PubMed: 20678471) »
  • Li J  et al. Misoprostol, an anti-ulcer agent and PGE2 receptor agonist, protects against cerebral ischemia. Neurosci Lett 438:210-5 (2008). Read more (PubMed: 18472336) »
  • Kiriyama M  et al. Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol 122:217-24 (1997). Read more (PubMed: 9313928) »

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