Anti-Milk Fat Globule 1抗体[SPM291], prediluted (ab54454)

概述

  • 产品名称Anti-Milk Fat Globule 1抗体[SPM291], prediluted
    参阅全部 Milk Fat Globule 1 一抗
  • 描述
    小鼠单克隆抗体[SPM291] to Milk Fat Globule 1, prediluted
  • 特异性We have data to indicate that this antibody may not cross react with Rat. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues.
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Tissue, cells or virus corresponding to Human Milk Fat Globule 1. Delipidated human milk fat globule membrane preparation.

  • 阳性对照
    • SKBR-3 cells. Breast, colon, or lung tissues.

性能

应用

Our Abpromise guarantee covers the use of ab54454 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: Ready-to-use for 30 min at RT.
    Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.
      Medin is the main constituent of aortic medial amyloid.
    • 组织特异性Mammary epithelial cell surfaces and aortic media. Overexpressed in several carcinomas.
    • 序列相似性Contains 1 EGF-like domain.
      Contains 2 F5/8 type C domains.
    • 翻译后修饰Medin has a ragged N-terminus with minor species starting at Pro-264 and Gly-273.
    • 细胞定位Membrane. Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • BA46 antibody
      • Breast epithelial antigen BA46 antibody
      • EDIL1 antibody
      • HMFG antibody
      • hP47 antibody
      • HsT19888 antibody
      • Lactadherin antibody
      • Medin antibody
      • MFG-E8 antibody
      • MFGE8 antibody
      • MFGM antibody
      • MFGM_HUMAN antibody
      • Milk fat globule EGF factor 8 antibody
      • Milk fat globule EGF factor 8 protein antibody
      • Milk fat globule-EGF factor 8 antibody
      • O acetyl disialoganglioside synthase antibody
      • OAcGD3S antibody
      • SED1 antibody
      • SPAG10 antibody
      • Sperm associated antigen 10 antibody
      • Sperm surface protein hP47 antibody
      see all

    Anti-Milk Fat Globule 1 antibody [SPM291], prediluted 图像

    • ab54454 (prediluted) staining Human Milk Fat Globule 1 in human colon by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.

    Anti-Milk Fat Globule 1 antibody [SPM291], prediluted (ab54454)参考文献

    ab54454 has not yet been referenced specifically in any publications.

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