Anti-Milk Fat Globule 1抗体[MFG-06] (ab2537)

概述

  • 产品名称Anti-Milk Fat Globule 1抗体[MFG-06]
    参阅全部 Milk Fat Globule 1 一抗
  • 描述
    小鼠单克隆抗体[MFG-06] to Milk Fat Globule 1
  • 特异性Reacts with 40-45 kDa glycoprotein in human milk fat globule membrane preparation.
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Tissue, cells or virus corresponding to Human Human Milk Fat Globule 1. Tissue/ cell preparation (Human). Milk fat globule membrane preparation.

性能

应用

Our Abpromise guarantee covers the use of ab2537 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
WB
  • 应用说明IHC-P: Use at an assay dependant concentration. Strongly positive on human epithelia-based structures.
    WB: Use at an assay dependant concentration.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.
      Medin is the main constituent of aortic medial amyloid.
    • 组织特异性Mammary epithelial cell surfaces and aortic media. Overexpressed in several carcinomas.
    • 序列相似性Contains 1 EGF-like domain.
      Contains 2 F5/8 type C domains.
    • 翻译后修饰Medin has a ragged N-terminus with minor species starting at Pro-264 and Gly-273.
    • 细胞定位Membrane. Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • BA46 antibody
      • Breast epithelial antigen BA46 antibody
      • EDIL1 antibody
      • HMFG antibody
      • hP47 antibody
      • HsT19888 antibody
      • Lactadherin antibody
      • Medin antibody
      • MFG-E8 antibody
      • MFGE8 antibody
      • MFGM antibody
      • MFGM_HUMAN antibody
      • Milk fat globule EGF factor 8 antibody
      • Milk fat globule EGF factor 8 protein antibody
      • Milk fat globule-EGF factor 8 antibody
      • O acetyl disialoganglioside synthase antibody
      • OAcGD3S antibody
      • SED1 antibody
      • SPAG10 antibody
      • Sperm associated antigen 10 antibody
      • Sperm surface protein hP47 antibody
      see all

    Anti-Milk Fat Globule 1 antibody [MFG-06] (ab2537)参考文献

    This product has been referenced in:
    • Bártková J  et al. Differentiation patterns of testicular germ-cell tumours as revealed by a panel of monoclonal antibodies. Tumour Biol 8:45-56 (1987). Read more (PubMed: 2440095) »

    See 1 Publication for this product

    Product Wall

    Nos anticorps anti hMFG1 sont des anticorps monoclonaux contre la protéine totale hMFG1, et nous ne savons pas ou se situe l'épitope. Cependant, j'ai effectué une recherche d'homologie entre les formes 1 et 8 et vous trouverez en attachement les résu...

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    Thank you for your enquiry and your patience. We do not know if it is due to glycosylation pattern of a single holoprotein or the antibody detects several proteins in that range. The WB image shows results in typical glycoprotein "smear" band of the in...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"