小鼠单克隆抗体[17-3-3.4] to MHC class II I E kappa (Biotin)
特异性ab25226 reacts with the I-Ek class II alloantigen on cells from mice of the H-2r haplotype; reactivity with H-2d and H-2p haplotypes has not been observed. Cells from mice of the H-2b, H-2f, H-2g7, H-2q,
and H-2s haplotypes do not express I-E antigen. can be used for complement-mediated cytotoxicity.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use 1µg for 106 cells. ab18454-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
相关性A major histocompatibility complex class II receptor. These display processed antigens from virally infected or transformed cells. Class II positive cells ('antigen presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re export the peptides (now bound to MHC class II protein) to the cell surface. These peptide MHC class II complexes can then be recognized by specific CD4+ lymphocytes.
细胞定位Type I membrane protein
H2 Ea antibody
Anti-MHC class II I E kappa antibody [17-3-3.4] (Biotin) (ab25226)参考文献
has not yet been referenced specifically in any publications.