Anti-MHC class II I E kappa抗体[17-3-3.4] (Biotin) (ab25226)

概述

  • 产品名称Anti-MHC class II I E kappa抗体[17-3-3.4] (Biotin)
    参阅全部 MHC class II I E kappa 一抗
  • 描述
    小鼠单克隆抗体[17-3-3.4] to MHC class II I E kappa (Biotin)
  • 偶联物Biotin
  • 特异性ab25226 reacts with the I-Ek class II alloantigen on cells from mice of the H-2r haplotype; reactivity with H-2d and H-2p haplotypes has not been observed. Cells from mice of the H-2b, H-2f, H-2g7, H-2q, and H-2s haplotypes do not express I-E antigen. can be used for complement-mediated cytotoxicity.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    C3H mouse skin graft and splenocytes.

  • 表位An epitope on mouse I-Ek MHC class II alloantigen.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.1% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度IgG fraction
  • 克隆单克隆
  • 克隆编号17-3-3.4
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab25226 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 1µg for 106 cells. ab18454-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

靶标

  • 相关性A major histocompatibility complex class II receptor. These display processed antigens from virally infected or transformed cells. Class II positive cells ('antigen presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re export the peptides (now bound to MHC class II protein) to the cell surface. These peptide MHC class II complexes can then be recognized by specific CD4+ lymphocytes.
  • 细胞定位Type I membrane protein
  • 别名
    • H2 Ea antibody
    • H2-Ea antibody

Anti-MHC class II I E kappa antibody [17-3-3.4] (Biotin) (ab25226)参考文献

ab25226 has not yet been referenced specifically in any publications.

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