Anti-MHC class II I E kappa抗体[14-4-4S] (Biotin) (ab93504)

概述

  • 产品名称
    Anti-MHC class II I E kappa抗体[14-4-4S] (Biotin)
    参阅全部 MHC class II I E kappa 一抗
  • 描述
    小鼠单克隆抗体[14-4-4S] to MHC class II I E kappa (Biotin)
  • 偶联物
    Biotin
  • 特异性
    ab93504 reacts with the mouse and rat MHC Class II, I-E subregion-encoded glycoprotein in mice strains of H-2k, H-2d, H-2p and H-2r. H-2f and H-2s haplotypes do not express the I-E antigen.
  • 经测试应用
    适用于: Flow Cytmore details
  • 种属反应性
    与反应: Mouse, Rat
  • 免疫原

    Tissue/ cell preparation: C3H mouse skin graft and splenocytes

  • 阳性对照
    • Mouse splenocytes
  • 常规说明


    The 14-4-4S monoclonal antibody has been reported to block antigen presentation in in vitro assays.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 0.09% Sodium Azide
    Constituents: PBS, 150mM Sodium chloride, pH 7.2
  • Concentration information loading...
  • 纯度
    Protein G purified
  • Primary antibody说明
    The 14-4-4S monoclonal antibody has been reported to block antigen presentation in in vitro assays.
  • 克隆
    单克隆
  • 克隆编号
    14-4-4S
  • 同种型
    IgG2a
  • 轻链类型
    kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab93504 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use at an assay dependent concentration. ab18454-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

靶标

  • 相关性
    A major histocompatibility complex class II receptor. These display processed antigens from virally infected or transformed cells. Class II positive cells ('antigen presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re export the peptides (now bound to MHC class II protein) to the cell surface. These peptide MHC class II complexes can then be recognized by specific CD4+ lymphocytes.
  • 细胞定位
    Type I membrane protein
  • 别名
    • H2 Ea antibody
    • H2-Ea antibody

文献

This product has been referenced in:
  • Spencer JS  et al. Expression and function of mixed isotype MHC class II molecules in normal mice. J Immunol 151:6822-32 (1993). Read more (PubMed: 8258692) »
  • Pruitt SK  et al. The effect of xenoreactive antibody and B cell depletion on hyperacute rejection of guinea pig-to-rat cardiac xenografts. Transplantation 56:1318-24 (1993). Read more (PubMed: 8278996) »

See all 4 Publications for this product

客户评价及客户问答

There are currently no Customer reviews or Questions for ab93504.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册