Anti-MHC class II I E kappa抗体[14-4-4S] (Biotin) (ab93504)

概述

  • 产品名称Anti-MHC class II I E kappa抗体[14-4-4S] (Biotin)
    参阅全部 MHC class II I E kappa 一抗
  • 描述
    小鼠单克隆抗体[14-4-4S] to MHC class II I E kappa (Biotin)
  • 偶联物Biotin
  • 特异性ab93504 reacts with the mouse and rat MHC Class II, I-E subregion-encoded glycoprotein in mice strains of H-2k, H-2d, H-2p and H-2r. H-2f and H-2s haplotypes do not express the I-E antigen.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Mouse, Rat
  • 免疫原

    Tissue/ cell preparation: C3H mouse skin graft and splenocytes

  • 阳性对照
    • Mouse splenocytes
  • 常规说明


    The 14-4-4S monoclonal antibody has been reported to block antigen presentation in in vitro assays.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS, 150mM Sodium chloride, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • Primary antibody说明The 14-4-4S monoclonal antibody has been reported to block antigen presentation in in vitro assays.
  • 克隆单克隆
  • 克隆编号14-4-4S
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab93504 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use at an assay dependent concentration. ab18454-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

靶标

  • 相关性A major histocompatibility complex class II receptor. These display processed antigens from virally infected or transformed cells. Class II positive cells ('antigen presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re export the peptides (now bound to MHC class II protein) to the cell surface. These peptide MHC class II complexes can then be recognized by specific CD4+ lymphocytes.
  • 细胞定位Type I membrane protein
  • 别名
    • H2 Ea antibody
    • H2-Ea antibody

Anti-MHC class II I E kappa antibody [14-4-4S] (Biotin) (ab93504)参考文献

This product has been referenced in:
  • Spencer JS  et al. Expression and function of mixed isotype MHC class II molecules in normal mice. J Immunol 151:6822-32 (1993). Read more (PubMed: 8258692) »
  • Pruitt SK  et al. The effect of xenoreactive antibody and B cell depletion on hyperacute rejection of guinea pig-to-rat cardiac xenografts. Transplantation 56:1318-24 (1993). Read more (PubMed: 8278996) »

See all 4 Publications for this product

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