概述

  • 产品名称
    Anti-MHC Class II I Ab抗体[OX-3]
  • 描述
    小鼠单克隆抗体[OX-3] to MHC Class II I Ab
  • 特异性
    ab63567 recognises a polymorphic determinant of rat Ia antigen (RT1Bu) present on Lewis, Wistar and AO strain rats but not BN, DA or PVG/c strains; reacts with mouse strains of MHC haplotypes b and s, and analysis of recombinant mouse strains showed that the determinants mapped to the I-A region; routinely tested in flow cytometry on Lewis rat splenocytes.
  • 经测试应用
    适用于: IHC-Fr, Flow Cyt, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat
  • 免疫原

    Rat thymocyte membrane glycoproteins

  • 阳性对照
    • Lewis rat splenocytes.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液
    Preservative: 0.09% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 纯化说明
    Purified IgG prepared by affinity chromatography from tissue culture supernatant.
  • 克隆
    单克隆
  • 克隆编号
    OX-3
  • 骨髓瘤
    NS1
  • 同种型
    IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab63567 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr
Flow Cyt
IHC-P
  • 应用说明
    Flow Cyt: 1/100. Use 10µl of the suggested working dilution to label 106) cells in 100µl.
    IHC-Fr: Use at an assay dependent dilution.
    IHC-P: Use at an assay dependent dilution. Does not require antigen retrieval methods.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 序列相似性
      Belongs to the MHC class II family.
      Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
    • 翻译后修饰
      Ubiquitinated in immature dendritic cells leading to down-regulation of MHC class II.
    • 细胞定位
      Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • A beta chain antibody
      • H-2 class II histocompatibility antigen antibody
      • H2 Ab1 antibody
      • H2 I A beta antibody
      • H2-Ab1 antibody
      • HB2A_MOUSE antibody
      • Histocompatibility 2 class II antigen A beta 1 antibody
      see all

    文献

    This product has been referenced in:
    • McMaster WR & Williams AF Monoclonal antibodies to Ia antigens from rat thymus: cross reactions with mouse and human and use in purification of rat Ia glycoproteins. Immunol Rev 47:117-37 (1979). Read more (PubMed: 398324) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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