Anti-MHC class I RT Ia抗体[MRC OX-27] (Biotin) (ab111923)

概述

  • 产品名称
    Anti-MHC class I RT Ia抗体[MRC OX-27] (Biotin)
    参阅全部 MHC class I RT Ia 一抗
  • 描述
    小鼠单克隆抗体[MRC OX-27] to MHC class I RT Ia (Biotin)
  • 偶联物
    Biotin
  • 特异性
    Cross-reactivity with Lewis rats have been shown to occur in some instances. ab111923 did not cross-react with Buffalo, Wistar, Fischer and ACI strains in Flow Cytometry.
  • 经测试应用
    适用于: Flow Cyt, IHC-Frmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    Phytohaemagglutinin Blasts.

  • 阳性对照
    • Rat Spleen cells (Brown Norway strain).

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 0.02% Sodium azide
    Constituents: 99% PBS, 0.5% BSA
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 纯化说明
    ab111923 was purified from ascitic fluid via Protein G Chromatography.
  • 克隆
    单克隆
  • 克隆编号
    MRC OX-27
  • 骨髓瘤
    P3-NS1/1-Ag4-1
  • 同种型
    IgG2a
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111923 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 0.5-1µg for 106 cells. ab97679-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
IHC-Fr Use at an assay dependent concentration.

靶标

  • 相关性
    The major histocompatibility complex (MHC) plays a central role in controlling immune responsiveness and susceptibility to a great variety of mainly autoimmune and infectious diseases. The mammalian MHC is usually divided into three regions, the class I, II, and III (also called central) gene regions, based on the genes contained therein. Class I regions encode the classical I (class Ia) and nonclassical I (class Ib) molecules. The widely expressed class Ia molecules perform the well described antigen presenting function to CD8 T lymphocytes, whereas the function of class Ib genes has largely remained unknown.
  • 细胞定位
    Secreted
  • 数据库链接
  • 别名
    • RT1 class I gene (A 1) antibody
    • RT1 class I gene antibody
    • RT1 class Ia locus A antibody
    • RT1 class Ia, locus A (A1) antibody
    • RT1 class Ia, locus A1 antibody
    • RT1.A1(N) antibody
    • RT1A 1 antibody
    • RT1A1 antibody
    see all

Anti-MHC class I RT Ia antibody [MRC OX-27] (Biotin) 图像

  • ab111923 at 1.0 µg/106 cells detecting MHC class I RT Ia in Brown Norway Rat spleen cells by Flow Cytometry. 98.9% more of the cells were stained than in the control (Biotin Mouse IgG2a).

Anti-MHC class I RT Ia antibody [MRC OX-27] (Biotin) (ab111923)参考文献

ab111923 has not yet been referenced specifically in any publications.

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Thank you for your email. We have the following references for Immunohistochemistry that may be of interest to you: Baker-Cairns, B.J. et al. 1996. Contributions of donor and host blood vessels in CNS allografts. Experimental Neurol...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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