Anti-MHC Class I H2 Dd抗体[34-5-8S] (Biotin) (ab25230)

概述

  • 产品名称Anti-MHC Class I H2 Dd抗体[34-5-8S] (Biotin)
    参阅全部 MHC Class I H2 Dd 一抗
  • 描述
    小鼠单克隆抗体[34-5-8S] to MHC Class I H2 Dd (Biotin)
  • 偶联物Biotin
  • 特异性It does not react with H2Dd alpha chains synthesized in vitro. Weak cross-reactivity with cells from mice of the H2b, H2q and H2s haplotypes has been observed by flow cytometric analysis. Reactivity with cells from mice of the H2f, H2k, H2p and H2r haplotypes has not been observed.
  • 经测试应用适用于: Flow Cyt, IP, Purification, Inhibition Assay, Othermore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    (C57BL/6 x DBA/2)F1 hybrid splenocytes (Mouse)

  • 表位ab25230 is specific for a conformational epitope found on the N-terminal domain of the alpha1 and alpha2 chains of mouse H2Dd class I alloantigen when complexed with beta2 microglobulin.
  • 常规说明


    ab25230 has been reported to block the recognition of H2Dd by Ly49A+, Ly49C+ and Ly49G2+ natural killer cells.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.1% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度IgG fraction
  • Primary antibody说明ab25230 has been reported to block the recognition of H2Dd by Ly49A+, Ly49C+ and Ly49G2+ natural killer cells.
  • 克隆单克隆
  • 克隆编号34-5-8S
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab25230 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use at an assay dependent concentration.

Use up to 1ug/106 cells.





ab18454-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
IP Use at an assay dependent concentration.
Purification Use at an assay dependent concentration.
Inhibition Assay Use at an assay dependent concentration.
Other Use at an assay dependent concentration.

Complement-dependent cytotoxicity.

靶标

  • 相关性MHC Class I H2 Dd is involved in the presentation of foreign antigens to the immune system.
  • 细胞定位Type I membrane protein.
  • 数据库链接
  • 别名
    • Class I major histocompatability complex antibody
    • H 2 class I histocompatibility antigen D D alpha chain antibody
    • H 2D antibody
    • H 2D cell surface glycoprotein antibody
    • H2 D antibody
    • H2 D(d) antibody
    • H2 D1 antibody
    • H2 DC1 beta transplantation antigen protein antibody
    • H2 L antibody
    • Histocompatibility 2 D region locus 1 antibody
    • MHC B7.2 antibody
    • MHC class I H2 antigen antibody
    • MHC class I heavy chain maturation peptide H 2D(d) antibody
    • MHC class I heavy chain maturation peptide H2 D(d) antibody
    • MHC class I heavy chain maturation peptide H2 Dd antibody
    • MHC class I polypeptide related sequence A antibody
    • MICA antibody
    • Q5k protein antibody
    see all

Anti-MHC Class I H2 Dd antibody [34-5-8S] (Biotin) (ab25230)参考文献

This product has been referenced in:
  • Brennan J  et al. Recognition of class I major histocompatibility complex molecules by Ly-49: specificities and domain interactions. J Exp Med 183:1553-9 (1996). Read more (PubMed: 8666913) »
  • Orihuela M  et al. The natural killer cell receptor Ly-49A recognizes a peptide-induced conformational determinant on its major histocompatibility complex class I ligand. Proc Natl Acad Sci U S A 93:11792-7 (1996). Read more (PubMed: 8876216) »

See all 8 Publications for this product

Product Wall

Ab25230 Anti-MHC Class I H2 Dd antibody [34-5-8S] (Biotin) in an alternate name for H2 D1 antibody.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"