生物素Anti-MHC class I抗体[AF6-88.5.5.3] (ab93528)
Key features and details
- Biotin Mouse monoclonal [AF6-88.5.5.3] to MHC class I
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: Biotin
- Isotype: IgG2a
概述
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产品名称
生物素Anti-MHC class I抗体[AF6-88.5.5.3]
参阅全部 MHC class I 一抗 -
描述
生物素小鼠单克隆抗体[AF6-88.5.5.3] to MHC class I -
宿主
Mouse -
偶联物
Biotin -
特异性
Reacts with the H-2Kb MHC class I alloantigen. Reactivity to other haplotypes (e.g. d, f, j, k, p, q, r, s, u, and v) has not been observed. -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse MHC class I. C57BL Mouse splenocytes.
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阳性对照
- Splenocytes
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.2
Preservative: 0.09% Sodium azide -
Concentration information loading...
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纯度
Affinity purified -
克隆
单克隆 -
克隆编号
AF6-88.5.5.3 -
同种型
IgG2a -
研究领域
相关产品
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab93528于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
说明 |
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Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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相关性
MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen. -
细胞定位
Cell Membrane; Type I membrane protein. -
别名
- A 28 antibody
- A 9 antibody
- Antigen presenting molecule antibody
see all
图片
数据表及文件
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Datasheet download
文献 (1)
ab93528 被引用在 1 文献中.
- Neek M et al. An Antigen-Delivery Protein Nanoparticle Combined with Anti-PD-1 Checkpoint Inhibitor Has Curative Efficacy in an Aggressive Melanoma Model. Adv Ther (Weinh) 3:N/A (2020). PubMed: 34141865