Anti-MHC Class 1 H2 Db抗体[27-11-13] (FITC) (ab25028)

概述

  • 产品名称
    Anti-MHC Class 1 H2 Db抗体[27-11-13] (FITC)
    参阅全部 MHC Class 1 H2 Db 一抗
  • 描述
    小鼠单克隆抗体[27-11-13] to MHC Class 1 H2 Db (FITC)
  • 偶联物
    FITC. Ex: 493nm, Em: 528nm
  • 特异性
    ab25028 recognizes with the a3 domain of H-2Db class I MHC antigen. The antibody cross-reacts with the a3 domain of H-2Ld, H-2Dq and H-2Lq, but not H-2Kd or H-2Dd. Reactivity with haplotypes k, f, p, r, and s has not been observed.
  • 经测试应用
    适用于: Flow Cyt, IHC-Fr, Functional Studiesmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Mouse C3H.SW splenocytes

  • 表位
    An epitope on the a chain of H-2Db

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C.
  • 存储溶液
    Preservative: 0.1% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    IgG fraction
  • 克隆
    单克隆
  • 克隆编号
    27-11-13
  • 同种型
    IgG2a
  • 轻链类型
    kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab25028 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 1µg for 106 cells. ab18455-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
IHC-Fr Use at an assay dependent concentration.
Functional Studies Use at an assay dependent concentration. (Complement-dependent cytoxicity assay)

靶标

  • 相关性
    In the mouse the MHC Class 1 loci are called H2K, H2L and H2D. The equivalent loci in the human MHC are HLA (Human Leukocyte Antigen). MHC class I molecules are heterodimers, consisting of a single transmembrane polypeptide chain (the a-chain) which is highly polymorphic, and the invariant ß2 microglobulin (which is encoded elsewhere, not in the MHC). MHC class I molecules are found on almost every nucleated cell of the body. Their major function is to present peptide fragments derived from antigens to cytotoxic T cells.
  • 细胞定位
    Cell Membrane; single pass type I membrane protein
  • 数据库链接
  • 别名
    • H 2D cell surface glycoprotein antibody
    • H2 class I histocompatibility antigen, DB alpha chain antibody
    • H2D(B) antibody
    • H2D1 antibody
    • Histocompatibility 2, D region locus 1 antibody
    see all

Anti-MHC Class 1 H2 Db antibody [27-11-13] (FITC) (ab25028)参考文献

ab25028 has not yet been referenced specifically in any publications.

Product Wall

Both ab21321 and ab25028 recognize extracellular epitopes and can be used to stain live cells for FACS.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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