Anti-MGP抗体(ab70193)

概述

  • 产品名称Anti-MGP抗体
    参阅全部 MGP 一抗
  • 描述
    小鼠多克隆抗体to MGP
  • 特异性This antibody is reactive against mammalian transfected lysate.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    MGP (AAH93078.1, 1 a.a. ~ 103 a.a) full-length human protein.

  • 阳性对照
    • Transfected 293T cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab70193 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 12 kDa (predicted molecular weight: 12 kDa).

靶标

  • 功能Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.
  • 疾病相关Defects in MGP are the cause of Keutel syndrome (KS) [MIM:245150]. KS is an autosomal recessive disorder characterized by abnormal cartilage calcification, peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia.
  • 序列相似性Belongs to the osteocalcin/matrix Gla protein family.
    Contains 1 Gla (gamma-carboxy-glutamate) domain.
  • 翻译后修饰Requires vitamin K-dependent gamma-carboxylation for its function.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cell growth inhibiting gene 36 protein antibody
    • Cell growth-inhibiting gene 36 protein antibody
    • GAMMA-CARBOXYGLUTAMIC ACID PROTEIN, MATRIX antibody
    • GIG36 antibody
    • Matrix Gla protein antibody
    • MGLAP antibody
    • MGP antibody
    • MGP_HUMAN antibody
    • NTI antibody
    see all

Anti-MGP antibody 图像

  • All lanes : Anti-MGP antibody (ab70193) at 1/500 dilution

    Lane 1 : MGP transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 12 kDa
    Observed band size : 12 kDa

Anti-MGP antibody (ab70193)参考文献

ab70193 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us.

The anti-MGP antibody (ab70193) has been raised against the full length MGP protein and as it is a polyclonal antibody the exact epitope cannot be determined.We would expect theantibodyto be able to detectboth for...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"