Anti-MGMT抗体(ab112504)

概述

  • 产品名称Anti-MGMT抗体
    参阅全部 MGMT 一抗
  • 描述
    兔多克隆抗体to MGMT
  • 经测试应用适用于: WB, ICCmore details
  • 种属反应性
    与反应: Rat, Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide corresponding to an internal sequence of Human MGMT.

性能

应用

Our Abpromise guarantee covers the use of ab112504 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 22 kDa.
ICC Use a concentration of 1 µg/ml.

靶标

  • 功能Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  • 序列相似性Belongs to the MGMT family.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 6 O methylguanine DNA methyltransferase antibody
    • 6-O-methylguanine-DNA methyltransferase antibody
    • Agat antibody
    • AGT antibody
    • AI267024 antibody
    • EC 2.1.1.63 antibody
    • Methylated DNA protein cysteine methyltransferase antibody
    • Methylated-DNA--protein-cysteine methyltransferase antibody
    • Methylguanine DNA methyltransferase antibody
    • MGC107020 antibody
    • MGMT antibody
    • MGMT_HUMAN antibody
    • O 6 methylguanine DNA alkyltransferase antibody
    • O 6 methylguanine DNA methyltransferase antibody
    • O-6-methylguanine-DNA methyltransferase antibody
    • O-6-methylguanine-DNA-alkyltransferase antibody
    see all

Anti-MGMT antibody 图像

  • All lanes : Anti-MGMT antibody (ab112504)

    Lane 1 : Rat brain tissue lysate
    Lane 2 : Rat liver tissue lysate
    Lane 3 : Rat spleen tissue lysate
    Lane 4 : Rat thymus tissue lysate
    Lane 5 : MCF-7 whole cell lysate
    Lane 6 : HeLa whole cell lysate
    Lane 7 : Jurkat whole cell lysate
    Lane 8 : Raji whole cell lysate


    Predicted band size : 22 kDa
    Observed band size : 25 kDa (why is the actual band size different from the predicted?)
  • ab112504 staining MGMT in Lung cancer by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).

Anti-MGMT antibody (ab112504)参考文献

ab112504 has not yet been referenced specifically in any publications.

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