概述

  • 产品名称Anti-MGAT5B抗体
  • 描述
    兔多克隆抗体to MGAT5B
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Rat
    预测可用于: Mouse, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Human
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 362-411 (EGPAPLEAIA NGCIFLQSRF SPPHSSLNHE FFRGKPTSRE VFSQHPYAEN) of Rat MGAT5B (NP_001100538.1).

  • 阳性对照
    • Rat Muscle Lysate

性能

应用

Our Abpromise guarantee covers the use of ab125403 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 90 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAcbeta1,2-Manalpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.
  • 组织特异性Predominantly expressed in brain. Expressed in all area of the adult and fetal brain Also expressed at much lower level in testis, spleen and thymus.
  • 通路Protein modification; protein glycosylation.
  • 序列相似性Belongs to the glycosyltransferase 18 family.
  • 细胞定位Golgi apparatus membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B antibody
    • 6-N-acetylglucosaminyltransferase B antibody
    • Alpha-1 antibody
    • Alpha-mannoside beta-1 antibody
    • GlcNAc-T Vb antibody
    • GNT-IX antibody
    • GNT-Vb antibody
    • hGnTVb antibody
    • Mannoside acetylglucosaminyltransferase 5B antibody
    • Mgat5b antibody
    • MGT5B_HUMAN antibody
    • N-acetylglucosaminyl-transferase Vb antibody
    • N-acetylglucosaminyltransferase IX antibody
    see all

Anti-MGAT5B antibody 图像

  • Anti-MGAT5B antibody (ab125403) at 1 µg/ml + Rat Muscle Lysate

    Predicted band size : 90 kDa

Anti-MGAT5B antibody (ab125403)参考文献

ab125403 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab125403.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"