概述

  • 产品名称
    Anti-MGAT5B抗体
  • 描述
    兔多克隆抗体to MGAT5B
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Rat
    预测可用于: Mouse, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Human
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 362-411 (EGPAPLEAIA NGCIFLQSRF SPPHSSLNHE FFRGKPTSRE VFSQHPYAEN) of Rat MGAT5B (NP_001100538.1).

  • 阳性对照
    • Rat Muscle Lysate

性能

应用

Our Abpromise guarantee covers the use of ab125403 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 90 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAcbeta1,2-Manalpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.
  • 组织特异性
    Predominantly expressed in brain. Expressed in all area of the adult and fetal brain Also expressed at much lower level in testis, spleen and thymus.
  • 通路
    Protein modification; protein glycosylation.
  • 序列相似性
    Belongs to the glycosyltransferase 18 family.
  • 细胞定位
    Golgi apparatus membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B antibody
    • 6-N-acetylglucosaminyltransferase B antibody
    • Alpha-1 antibody
    • Alpha-mannoside beta-1 antibody
    • GlcNAc-T Vb antibody
    • GNT-IX antibody
    • GNT-Vb antibody
    • hGnTVb antibody
    • Mannoside acetylglucosaminyltransferase 5B antibody
    • Mgat5b antibody
    • MGT5B_HUMAN antibody
    • N-acetylglucosaminyl-transferase Vb antibody
    • N-acetylglucosaminyltransferase IX antibody
    see all

Anti-MGAT5B antibody 图像

  • Anti-MGAT5B antibody (ab125403) at 1 µg/ml + Rat Muscle Lysate

    Predicted band size : 90 kDa

实验方案

Anti-MGAT5B antibody (ab125403)参考文献

ab125403 has not yet been referenced specifically in any publications.

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