概述

  • 产品名称Anti-MFSD8抗体
  • 描述
    兔多克隆抗体to MFSD8
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 351-400 (FFILLPWGNQ FPKIQWEDLH NNSIPNTTFG EIIIGLWKSP MEDDNERPTG) of human MFSD8 (NP_689991).

  • 阳性对照
    • HepG2 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab108231 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 57 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能May be a carrier that transport small solutes by using chemiosmotic ion gradients.
  • 组织特异性Expressed at very low levels in all tissues tested.
  • 疾病相关Defects in MFSD8 are the cause of neuronal ceroid lipofuscinosis type 7 (CLN7) [MIM:610951]. A form of late infantile neuronal ceroid lipofuscinosis. CNL are a clinically and genetically heterogeneous group of neurodegenerative disorders characterized by the intracellular accumulation of autofluorescent lipopigment storage material in different patterns ultrastructurally. The patterns most often observed CLN7 are mixed combinations of granular, curvilinear, fingerprint, and rectilinear profiles. The clinical course includes progressive dementia, seizures, and progressive visual failure.
  • 序列相似性Belongs to the major facilitator superfamily.
  • 细胞定位Lysosome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Ceroid-lipofuscinosis neuronal protein 7 antibody
    • CLN7 antibody
    • Major facilitator superfamily domain-containing protein 8 antibody
    • MFSD8 antibody
    • MFSD8_HUMAN antibody
    see all

Anti-MFSD8 antibody 图像

  • Anti-MFSD8 antibody (ab108231) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Predicted band size : 57 kDa

Anti-MFSD8 antibody (ab108231)参考文献

ab108231 has not yet been referenced specifically in any publications.

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