概述

  • 产品名称Anti-METTL1抗体
    参阅全部 METTL1 一抗
  • 描述
    小鼠多克隆抗体to METTL1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length Human METTL1, amino acids 1-276 (AAH00550)

  • 阳性对照
    • Human placenta tissue lysate, METTL1 transfected 293T cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab88912 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 31 kDa.

靶标

  • 功能Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  • 组织特异性Ubiquitous.
  • 通路tRNA modification; N(7)-methylguanine-tRNA biosynthesis.
  • 序列相似性Belongs to the methyltransferase superfamily. TrmB family.
  • 翻译后修饰Phosphorylation at Ser-27 inactivates its catalytic activity but does not affect the interaction with WDR4.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C12orf1 antibody
    • D1075 like gene product antibody
    • FLJ95748 antibody
    • Methyltransferase like 1 antibody
    • Methyltransferase like protein 1 antibody
    • Methyltransferase-like protein 1 antibody
    • Mettl1 antibody
    • TRM8 antibody
    • TRMB_HUMAN antibody
    • TRMT8 antibody
    • tRNA (guanine N(7) ) methyltransferase antibody
    • tRNA (guanine(46)-N(7))-methyltransferase antibody
    • tRNA (guanine-N(7)-)-methyltransferase antibody
    • tRNA(m7G46) methyltransferase antibody
    • tRNA(m7G46)-methyltransferase antibody
    • YDL201w antibody
    see all

Anti-METTL1 antibody 图像

  • Anti-METTL1 antibody (ab88912) at 1/500 dilution + Human placenta tissue lysate at 50 µg

    Predicted band size : 31 kDa
    Observed band size : 27 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-METTL1 antibody (ab88912) at 1/500 dilution

    Lane 1 : METTL1 transfected 293T cell lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 31 kDa
    Observed band size : 31 kDa

Anti-METTL1 antibody (ab88912)参考文献

ab88912 has not yet been referenced specifically in any publications.

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