Anti-Metabotropic Glutamate Receptor 5抗体(ab76561)

概述

  • 产品名称Anti-Metabotropic Glutamate Receptor 5抗体
    参阅全部 Metabotropic Glutamate Receptor 5 一抗
  • 描述
    小鼠单克隆抗体to Metabotropic Glutamate Receptor 5
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Mouse, Rat, Horse, Chicken, Dog, Human, Chimpanzee
  • 免疫原

    Recombinant fragment: CPGYAGLCDA MKPIDGRKLL ESLMKTNFTG VSGDTILFDE NGDSPGRYEI MNFKEMGKD YFDYINVGSW DNGELKMDDD EVWSKKSNII RSVCSEPCEK G, corresponding to amino acids 419-519 of Human Metabotropic Glutamate Receptor 5 (NP_000833) with a tag of 26 kDa.

  • 阳性对照
    • Recombinant tagged Human Metabotropic Glutamate Receptor 5 fragment.

性能

应用

Our Abpromise guarantee covers the use of ab76561 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 132 kDa.
ELISA Use at an assay dependent dilution. Detection limit for recombinant tagged Metabotropic Glutamate Receptor 5 is approximately 0.03ng/ml as a capture antibody.

靶标

  • 功能G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.
  • 序列相似性Belongs to the G-protein coupled receptor 3 family.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Glutamate receptor metabotropic 5 antibody
    • GPRC1E antibody
    • Grm5 antibody
    • GRM5_HUMAN antibody
    • Metabotropic glutamate receptor 5 antibody
    • Metabotropic glutamate receptor 5 variant F antibody
    • Metabotropic glutamate receptor 5 variant G antibody
    • Metabotropic glutamate receptor 5 variant H antibody
    • mGlu5 antibody
    • mGluR5 antibody
    • PPP1R86 antibody
    • Protein phosphatase 1 regulatory subunit 86 antibody
    see all

Anti-Metabotropic Glutamate Receptor 5 antibody 图像

  • Anti-Metabotropic Glutamate Receptor 5 antibody (ab76561) at 1 µg/ml + Recombinant tagged Human Metabotropic Glutamate Receptor 5 fragment at 0.1 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

    Predicted band size : 132 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)

Anti-Metabotropic Glutamate Receptor 5 antibody (ab76561)参考文献

ab76561 has not yet been referenced specifically in any publications.

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