概述

  • 产品名称
    Anti-Mesothelin抗体
    参阅全部 Mesothelin 一抗
  • 描述
    兔多克隆抗体to Mesothelin
  • 经测试应用
    适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant protein fragment corresponding to a region within amino acids 44 and 438 of Human Mesothelin (NP_037536).

  • 阳性对照
    • WB: 293T cell lysate IHC-P: serous OVCA

性能

应用

Our Abpromise guarantee covers the use of ab96869 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 69 kDa.
IHC-P 1/100.

靶标

  • 功能
    Membrane-anchored forms may play a role in cellular adhesion.
    Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.
  • 组织特异性
    Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level).
  • 疾病相关
    Note=Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer.
  • 序列相似性
    Belongs to the mesothelin family.
  • 翻译后修饰
    Both MPF and the cleaved form of mesothelin are N-glycosylated.
    Proteolytically cleaved by a furin-like convertase to generate megakaryocyte-potentiating factor (MPF), and the cleaved form of mesothelin.
  • 细胞定位
    Secreted and Cell membrane. Golgi apparatus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CAK 1 antibody
    • CAK1 antibody
    • CAK1 antigen antibody
    • cleaved form antibody
    • Megakaryocyte potentiating factor antibody
    • Mesothelin antibody
    • Mesothelin isoform 1 precursor antibody
    • MPF antibody
    • Msln antibody
    • MSLN_HUMAN antibody
    • Pre pro megakaryocyte potentiating factor antibody
    • Pre-pro-megakaryocyte-potentiating factor antibody
    • SMR antibody
    • SMRP antibody
    • Soluble MPF mesothelin related protein antibody
    see all

图片

  • Anti-Mesothelin antibody (ab96869) at 1/1000 dilution + 293T whole cell lysate at 30 µg

    Predicted band size : 69 kDa
  • Immunohistochemical analysis of Mesothelin in paraffin embedded serous OVCA, using ab96869 at a 1/100 dilution.

文献

ab96869 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab96869.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册