概述

  • 产品名称Anti-Mephalan抗体[MP5/73]
  • 描述
    大鼠单克隆抗体[MP5/73] to Mephalan
  • 特异性This antibody was developed to improve detection of melphalan-DNA adducts through its ability to recognise the stabilised adduct. This antibodiy can be used for quantification of melphalan adducts in purified DNA by ELISA and for immunofluorescent detection of melphalan-DNA adducts in single cells.
  • 经测试应用适用于: ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Native DNA reacted with melphalan.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度IgG fraction
  • 克隆单克隆
  • 克隆编号MP5/73
  • 骨髓瘤Y3/Ag1.2.3
  • 同种型IgG2b
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab97892 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.

靶标

  • 相关性Mephalan hydrochloride is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents.

Anti-Mephalan antibody [MP5/73] (ab97892)参考文献

This product has been referenced in:
  • Rothbarth J  et al. Immunohistochemical detection of melphalan-DNA adducts in colon cancer cells in vitro and human colorectal liver tumours in vivo. Biochem Pharmacol 67:1771-8 (2004). Read more (PubMed: 15081876) »
  • Frank AJ & Tilby MJ Quantification of DNA adducts in individual cells by immunofluorescence: effects of variation in DNA conformation. Exp Cell Res 283:127-34 (2003). Read more (PubMed: 12581733) »

See all 3 Publications for this product

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