Anti-MELK抗体- C-terminal (ab71287)

概述

  • 产品名称Anti-MELK抗体- C-terminal
    参阅全部 MELK 一抗
  • 描述
    兔多克隆抗体to MELK - C-terminal
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 阳性对照
    • HEPG2 tissue lysate.

性能

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应用

Our Abpromise guarantee covers the use of ab71287 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 75 kDa (predicted molecular weight: 75 kDa).

靶标

  • 功能Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis.
  • 组织特异性Expressed in placenta, kidney, thymus, testis, ovary and intestine.
  • 序列相似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
    Contains 1 KA1 (kinase-associated) domain.
    Contains 1 protein kinase domain.
  • 翻译后修饰Autophosphorylated. Thr-478 phosphorylation during mitosis promotes interaction with PPP1R8.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AI327312 antibody
    • hMELK antibody
    • HPK 38 antibody
    • hPK38 antibody
    • KIAA0175 antibody
    • Likely ortholog of maternal embryonic leucine zipper kinase antibody
    • Maternal embryonic leucine zipper kinase antibody
    • MELK antibody
    • MELK_HUMAN antibody
    • mKIAA0175 antibody
    • MPK38 antibody
    • OTTHUMP00000021377 antibody
    • OTTHUMP00000046113 antibody
    • pEg3 kinase antibody
    • Protein kinase Eg3 antibody
    • Protein kinase PK38 antibody
    • RP23 382O11.1 antibody
    • Tyrosine protein kinase MELK antibody
    see all

Anti-MELK antibody - C-terminal 图像

  • Anti-MELK antibody - C-terminal (ab71287) at 1/100 dilution + HEPG2 tissue lysate at 12.5 µg

    Predicted band size : 75 kDa
    Observed band size : 75 kDa
    Additional bands at : 20 kDa,50 kDa. We are unsure as to the identity of these extra bands.

Anti-MELK antibody - C-terminal (ab71287)参考文献

ab71287 has not yet been referenced specifically in any publications.

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