Anti-Melanoma Associated Antigen 100+ / 25kDa抗体[NKI/C3] (ab36616)

概述

  • 产品名称Anti-Melanoma Associated Antigen 100+ / 25kDa抗体[NKI/C3]
    参阅全部 Melanoma Associated Antigen 100+ / 25kDa 一抗
  • 描述
    小鼠单克隆抗体[NKI/C3] to Melanoma Associated Antigen 100+ / 25kDa
  • 特异性Ab36616 is specific to Melanoma Associated Antigen 100+ / 7 kDa. It reacts with some mucus producing tumors, carcinoids, carcinomas of the thyroid, mast cells, histiocytes in tumor regions and with cells with secretory functions such as salivary glands, bronchial glands, sweat glands, pancreas and prostate.
  • 经测试应用适用于: IHC-Pmore details
    不适用于: IHC-Fr
  • 种属反应性
    与反应: Human
  • 免疫原

    The details of the immunogen for this antibody are not available.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 15mM Sodium Azide
    Constituents: 1% BSA, 50mM PBS, pH 7.4
  • Concentration information loading...
  • 纯度Ascites
  • 纯化说明This antibody was purified by centrifugation.
  • 克隆单克隆
  • 克隆编号NKI/C3
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab36616 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/5 - 1/20.
  • 应用说明Is unsuitable for IHC-Fr.
  • 靶标

    • 相关性Melanoma-associated antigens (MAAs) are highly immunogenic human antigens that are recognized by cytotoxic T lymphocytes (CTLs). Both ocular and skin melanomas are derived from normal melanocytes that originate from the neural crest, although the melanocytes of the eye are functionally and morphologically distinct. Both types of melanomas carry a wide range of MAAs. Melanoma Associated Antigen 100+ / 25kDa is mainly present in the cytoplasm of melanoma cells and nevocellular nevi.
    • 别名
      • Melanoma Associated Antigen antibody

    Anti-Melanoma Associated Antigen 100+ / 25kDa antibody [NKI/C3] 图像

    • Paraffin-embedded human skin tissue section subjected to IHC staining of MUM1 using ab36616 in the ABC method.

    Anti-Melanoma Associated Antigen 100+ / 25kDa antibody [NKI/C3] (ab36616)参考文献

    This product has been referenced in:
    • Fernando SS  et al. Immunohistochemical analysis of cutaneous malignant melanoma: comparison of S-100 protein, HMB-45 monoclonal antibody and NKI/C3 monoclonal antibody. Pathology 26:16-9 (1994). Read more (PubMed: 8165017) »

    See 1 Publication for this product

    Product Wall

    Generally we have found that staining like you are describing, with areas of strong and weak signal, are result of incomplete fixation or antigen retrieval. We would recommend first to ensure complete fixation of the tissue. I would be happy to review ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"