概述

  • 产品名称
  • 描述
    兔多克隆抗体to MEKK2
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Rat, Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide corresponding to the C-terminal sequence of Human MEKK2. Rat and Mouse sequences differ by one amino acid.

  • 阳性对照
    • Rat brain tissue lysate, Rat testicular tissus lysate, Rat lung tissue lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
    Constituents: 0.1% Dibasic monohydrogen sodium phosphate, 0.45% Sodium chloride, 2.5% BSA, 96.9% Water
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab125223 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 70 kDa. The detection limit is approximately 1ng/lane under non-reducing and reducing conditions.

靶标

  • 功能
    Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 (By similarity). Plays a role in caveolae kiss-and-run dynamics.
  • 序列相似性
    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    Contains 1 OPR domain.
    Contains 1 protein kinase domain.
  • 翻译后修饰
    Autophosphorylated.
  • 细胞定位
    Cytoplasm. Nucleus. Upon EGF stimulation, translocates into the nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • M3K2_HUMAN antibody
    • Map3k2 antibody
    • MAPK/ERK kinase kinase 2 antibody
    • MEK kinase 2 antibody
    • MEKK 2 antibody
    • MEKK2b antibody
    • Mitogen activated protein kinase kinase kinase 2 antibody
    • Mitogen-activated protein kinase kinase kinase 2 antibody
    see all

Anti-MEKK2 antibody 图像

  • All lanes : Anti-MEKK2 antibody (ab125223) at 1 µg/ml

    Lane 1 : Rat brain tissue lysate
    Lane 2 : Rat testicular tissue lysate
    Lane 3 : Rat lung tissue lysate


    Predicted band size : 70 kDa

实验方案

Anti-MEKK2 antibody (ab125223)参考文献

ab125223 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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