概述

  • 产品名称Anti-MEKK2抗体
    参阅全部 MEKK2 一抗
  • 描述
    兔多克隆抗体to MEKK2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 13-43 of Mouse MEKK2.

  • 阳性对照
    • 293 cell lysates, transiently transfected with the MEKK2 gene.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab116348 is purified through a Protein A column, followed by peptide affinity purification.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab116348 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 70 kDa.

靶标

  • 功能Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 (By similarity). Plays a role in caveolae kiss-and-run dynamics.
  • 序列相似性Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    Contains 1 OPR domain.
    Contains 1 protein kinase domain.
  • 翻译后修饰Autophosphorylated.
  • 细胞定位Cytoplasm. Nucleus. Upon EGF stimulation, translocates into the nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • M3K2_HUMAN antibody
    • Map3k2 antibody
    • MAPK/ERK kinase kinase 2 antibody
    • MEK kinase 2 antibody
    • MEKK 2 antibody
    • MEKK2b antibody
    • Mitogen activated protein kinase kinase kinase 2 antibody
    • Mitogen-activated protein kinase kinase kinase 2 antibody
    see all

Anti-MEKK2 antibody 图像

  • All lanes : Anti-MEKK2 antibody (ab116348) at 1/100 dilution

    Lane 1 : 293 cell lysates, non-transfected
    Lane 2 : 293 cell lysates, MEKK2 transfected

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 70 kDa

Anti-MEKK2 antibody (ab116348)参考文献

ab116348 has not yet been referenced specifically in any publications.

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