概述

  • 产品名称Anti-MEK6抗体
    参阅全部 MEK6 一抗
  • 描述
    兔多克隆抗体to MEK6
  • 经测试应用适用于: WB, IP, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Xenopus laevis
  • 免疫原

    Synthetic peptide derived from a sequence near the carboxy-terminus of Human MEK6, conjugated to KLH.

  • 阳性对照
    • Human liver and tonsil tissue and Mouse brain tissue extract.

性能

应用

Our Abpromise guarantee covers the use of ab110629 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. Predicted molecular weight: 37 kDa.
IP Use at an assay dependent concentration.
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38 exclusively.
  • 组织特异性Isoform 2 is only expressed in skeletal muscle. Isoform 1 is expressed in skeletal muscle, heart, and in lesser extent in liver or pancreas.
  • 序列相似性Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
    Contains 1 protein kinase domain.
  • 翻译后修饰Weakly autophosphorylated.
    Acetylation of Ser-207 and Thr-211 by Yersinia yopJ prevents phosphorylation and activation, thus blocking the MAPK signaling pathway.
  • Information by UniProt
  • 数据库链接
  • 形式It localizes to nucleus, cytoplasm and cytoskeleton. Note: Binds to microtubules.
  • 别名
    • Dual specificity mitogen activated protein kinase kinase 6 antibody
    • Dual specificity mitogen-activated protein kinase kinase 6 antibody
    • MAP kinase kinase 6 antibody
    • MAP2K6 antibody
    • MAPK/ERK kinase 6 antibody
    • MAPKK 6 antibody
    • MAPKK6 antibody
    • MEK 6 antibody
    • MEK6 antibody
    • Mitogen Activated Protein Kinase Kinase 6 antibody
    • MKK 6 antibody
    • MKK6 antibody
    • MP2K6_HUMAN antibody
    • PRKMK6 antibody
    • Protein kinase mitogen activated kinase 6 antibody
    • protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6) antibody
    • SAPK kinase 3 antibody
    • SAPKK-3 antibody
    • SAPKK3 antibody
    • SKK3 antibody
    • Stress-activated protein kinase kinase 3 antibody
    see all

Anti-MEK6 antibody 图像

  • Immunohistological staining of Human Liver, Formalin-Fixed, Paraffin-Embedded tissue using ab110629 at 10µg/ml dilution.
  • Immunohistological staining of Human Tonsil, Formalin-Fixed, Paraffin-Embedded tissue using ab110629 at 10µg/ml dilution.
  • Anti-MEK6 antibody (ab110629) + Mouse brain tissue extract

    Predicted band size : 37 kDa

Anti-MEK6 antibody (ab110629)参考文献

ab110629 has not yet been referenced specifically in any publications.

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