概述

  • 产品名称
    Anti-MEK4抗体[7A6]
    参阅全部 MEK4 一抗
  • 描述
    小鼠单克隆抗体[7A6] to MEK4
  • 经测试应用
    适用于: IHC-Pmore details
    不适用于: IHC-Fr or WB
  • 种属反应性
    与反应: Human
  • 免疫原

    Prokaryotic recombinant fusion protein corresponding to a 116 amino acid portion of the C-terminus of the human MKK4 molecule.

  • 阳性对照
    • Testis.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液
    Preservative: 15mM Sodium Azide
    Constituents: Tissue culture supernatant
  • 纯度
    Tissue culture supernatant
  • 克隆
    单克隆
  • 克隆编号
    7A6
  • 骨髓瘤
    P3-NS1/1-Ag4-1
  • 同种型
    IgG2a
  • 轻链类型
    kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab49466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration.
  • 应用说明
    Is unsuitable for IHC-Fr or WB.
  • 靶标

    • 功能
      Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).
    • 组织特异性
      Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
    • 序列相似性
      Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
      Contains 1 protein kinase domain.
    • 翻译后修饰
      Activated by phosphorylation on Ser/Thr by MAP kinase kinase kinases.
    • Information by UniProt
    • 数据库链接
    • 别名
      • c Jun N terminal kinase kinase 1 antibody
      • C-JUN N-terminal kinase kinase 1 antibody
      • Dual specificity mitogen activated protein kinase kinase 4 antibody
      • Dual specificity mitogen-activated protein kinase kinase 4 antibody
      • JNK Activated Kinase 1 antibody
      • JNK activating kinase 1 antibody
      • JNK-activating kinase 1 antibody
      • JNKK antibody
      • JNKK1 antibody
      • MAP kinase kinase 4 antibody
      • Map2k4 antibody
      • MAPK ERK kinase 4 antibody
      • MAPK/ERK kinase 4 antibody
      • MAPKK 4 antibody
      • MAPKK4 antibody
      • MEK 4 antibody
      • MEK4 antibody
      • Mitogen activated protein kinase kinase 4 antibody
      • MKK 4 antibody
      • MKK4 antibody
      • MP2K4_HUMAN antibody
      • PRKMK4 antibody
      • SAPK ERK kinase 1 antibody
      • SAPK/ERK kinase 1 antibody
      • SAPKK 1 antibody
      • SAPKK1 antibody
      • SEK1 antibody
      • SERK1 antibody
      • SKK1 antibody
      • Stress activated protein kinase kinase 1 antibody
      see all

    Anti-MEK4 antibody [7A6] 图像

    • Ab49466, at a dilution of 1/20, staining MKK4 in paraffin sections of human testis by Immunohistochemistry.
      Note cytoplasmic and nuclear staining of spermatogonia in the seminiferous tubules.

    Anti-MEK4 antibody [7A6] (ab49466)参考文献

    ab49466 has not yet been referenced specifically in any publications.

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