Anti-MEK4抗体[2D10D8,4G11B2] (ab60017)

概述

  • 产品名称
    Anti-MEK4抗体[2D10D8,4G11B2]
    参阅全部 MEK4 一抗
  • 描述
    小鼠单克隆抗体[2D10D8,4G11B2] to MEK4
  • 经测试应用
    适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein

  • 阳性对照
    • IHC-P: Human thymoma tissue or human spleen tissue.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 纯度
    Protein A purified
  • 克隆
    单克隆
  • 克隆编号
    2D10D8,4G11B2
  • 同种型
    IgM
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab60017 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 44 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA 1/10000.
IHC-P Use at an assay dependent dilution.

靶标

  • 功能
    Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).
  • 组织特异性
    Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
  • 序列相似性
    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
    Contains 1 protein kinase domain.
  • 翻译后修饰
    Activated by phosphorylation on Ser/Thr by MAP kinase kinase kinases.
  • Information by UniProt
  • 数据库链接
  • 别名
    • c Jun N terminal kinase kinase 1 antibody
    • C-JUN N-terminal kinase kinase 1 antibody
    • Dual specificity mitogen activated protein kinase kinase 4 antibody
    • Dual specificity mitogen-activated protein kinase kinase 4 antibody
    • JNK Activated Kinase 1 antibody
    • JNK activating kinase 1 antibody
    • JNK-activating kinase 1 antibody
    • JNKK antibody
    • JNKK1 antibody
    • MAP kinase kinase 4 antibody
    • Map2k4 antibody
    • MAPK ERK kinase 4 antibody
    • MAPK/ERK kinase 4 antibody
    • MAPKK 4 antibody
    • MAPKK4 antibody
    • MEK 4 antibody
    • MEK4 antibody
    • Mitogen activated protein kinase kinase 4 antibody
    • MKK 4 antibody
    • MKK4 antibody
    • MP2K4_HUMAN antibody
    • PRKMK4 antibody
    • SAPK ERK kinase 1 antibody
    • SAPK/ERK kinase 1 antibody
    • SAPKK 1 antibody
    • SAPKK1 antibody
    • SEK1 antibody
    • SERK1 antibody
    • SKK1 antibody
    • Stress activated protein kinase kinase 1 antibody
    see all

Anti-MEK4 antibody [2D10D8,4G11B2] 图像

  • Ab60017 (1:500) staining human MKK4 in lymphocyte of human thymoma tissue by immunohistochemistry using paraffin embedded tissue. Cytoplasmic localization is shown using DAB staining.
  • Ab60017 (1:500) staining human MKK4 in human spleen tissue by immunohistochemistry using paraffin embedded tissue. Cytoplasmic localization is shown using DAB staining.

Anti-MEK4 antibody [2D10D8,4G11B2] (ab60017)参考文献

ab60017 has not yet been referenced specifically in any publications.

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