概述

  • 产品名称Anti-MEF2B抗体
    参阅全部 MEF2B 一抗
  • 描述
    兔多克隆抗体to MEF2B
  • 经测试应用适用于: WB, EMSA, IPmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 234-365 of Human MEF2B

性能

应用

Our Abpromise guarantee covers the use of ab33540 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 39 kDa.
EMSA Use at an assay dependent dilution. Use 0.1µl per sample.
IP Use at an assay dependent dilution. Use 4µl for 1ml cell lysate.

靶标

  • 功能Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription.
  • 组织特异性Expressed in skeletal and cardiac muscle and brain.
  • 序列相似性Belongs to the MEF2 family.
    Contains 1 MADS-box domain.
    Contains 1 Mef2-type DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MADS box transcription enhancer factor 2 antibody
    • MDS1 EVI1 antibody
    • Mef2b antibody
    • MEF2B_HUMAN antibody
    • Myocyte enhancer factor 2B antibody
    • Myocyte specific enhancer factor 2B antibody
    • Myocyte-specific enhancer factor 2B antibody
    • PRDM3 antibody
    • RSRFR2 antibody
    • Serum response factor like protein 2 antibody
    • Serum response factor-like protein 2 antibody
    • XMEF2 antibody
    see all

Anti-MEF2B antibody (ab33540)参考文献

This product has been referenced in:
  • Yao L  et al. Activation of transcription factor MEF2D by bis(3)-cognitin protects dopaminergic neurons and ameliorates Parkinsonian motor defects. J Biol Chem 287:34246-55 (2012). WB . Read more (PubMed: 22891246) »
  • Chang AY  et al. Calcineurin mediates bladder wall remodeling secondary to partial outlet obstruction. Am J Physiol Renal Physiol 301:F813-22 (2011). EMSA ; Mouse . Read more (PubMed: 21775483) »

See all 4 Publications for this product

Product Wall

The immunogen of ab33540 derives from the protein MEF2B isoform b, http://www.ncbi.nlm.nih.gov/protein/5174543. It is originally from the gene RSRFR2 described in Pollack and Treisman, Genes and Development 1991.

The immunogen sequence is aa 2...

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Muchas gracias por tomarte la molestia de mandarnos el cuestionario y las imágenes.

He estudiado el protocolo enviado, y hay una serie de sugerencias que me gustaría haceros para intentar mejorar los resultados del anticuerpo. <...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"