Anti-Measles phosphoprotein抗体[9H4] (ab43820)

概述

  • 产品名称
    Anti-Measles phosphoprotein抗体[9H4]
  • 描述
    小鼠单克隆抗体[9H4] to Measles phosphoprotein
  • 经测试应用
    适用于: ELISA, WB, ICC/IFmore details
  • 种属反应性
    Measles virus. Does not react with other viruses.
  • 免疫原

    Recombinant phosphoprotein.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Constituents: 0.75% Glycine, 1.21% Tris, 2% Sucrose
  • Concentration information loading...
  • 纯度
    Protein A purified
  • 克隆
    单克隆
  • 克隆编号
    9H4
  • 同种型
    IgG1
  • 轻链类型
    kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab43820 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/2000 - 1/10000.
WB 1/200 - 1/1000. Predicted molecular weight: 70 kDa.
ICC/IF 1/100 - 1/500.

靶标

  • 相关性
    Measles virus belongs to the Paramyxoviridae family within the Mononegavirales order. Measles phosphoprotein is an essential component of the RNA polymerase and the nascent chain assembly complex. The non-segmented, single stranded, negative sense RNA genome of the virus is encapsidated by the nucleoprotein (N) to form a helical nucleocapsid. This ribonucleoproteic complex is the substrate for both transcription and replication. The RNA-dependent RNA polymerase binds to the nucleocapsid template via its co-factor, the phosphoprotein (P).
  • 别名
    • measles virus antibody
    • subacute sclerose panencephalitis virus antibody

文献

This product has been referenced in:
  • Chung HK  et al. Tunable and reversible drug control of protein production via a self-excising degron. Nat Chem Biol 11:713-20 (2015). Read more (PubMed: 26214256) »
  • Krumm SA  et al. The measles virus nucleocapsid protein tail domain is dispensable for viral polymerase recruitment and activity. J Biol Chem 288:29943-53 (2013). WB . Read more (PubMed: 24003217) »

See all 2 Publications for this product

客户评价及客户问答

The monoclonal antibody ab43820 is raised against full-length recombinant phosphoprotein, but the single epitope it recognizes has not been mapped, so we cannot predict whether the mutations you have introduced will interfere with detection by ab43820....

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Thank you for your inquiry.

Please excuse the delay in my answer. I was waiting for more in formation from the source of this antibody.

They now confirmed that ab43820 binds to the phosphorylated protein only.

The un-phosp...

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Thank you for contacting us.

The antibody ab43820 is against phophorylated form of protein. I would suggest other antibodiers in case customer is interested in detecting unphosphorylated form of measles.

ab23974; ab106292; ab101015...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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