Anti-Measles nucleoprotein抗体[2F3] (ab106292)

概述

  • 产品名称
    Anti-Measles nucleoprotein抗体[2F3]
    参阅全部 Measles nucleoprotein 一抗
  • 描述
    小鼠单克隆抗体[2F3] to Measles nucleoprotein
  • 经测试应用
    适用于: ICC/IF, ICC, WB, ELISAmore details
  • 种属反应性
    与反应: Other
  • 免疫原

    Recombinant Nucleoprotein

性能

应用

Our Abpromise guarantee covers the use of ab106292 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent dilution.
ICC 1/100 - 1/500.
WB 1/200 - 1/1000. Predicted molecular weight: 58 kDa.
ELISA 1/2000 - 1/10000.

靶标

  • 相关性
    Involved in the encapsidating of the genome in a ratio of 1 N per 6 ribonucleotides, resulting in the protection from nucleases. The nucleocapsid (NC) has an helical structure with either 12.35 or 11.64 N per turn, approximately 20nm in diameter, with a hollow central cavity approximately 5nm in diameter. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases. N is released in the blood following lysis of measles infected cells, it interacts then with human FCGR2B on immune cells, inducing apoptosis and blocking inflammatory immune response. Ntail binds to a protein on human thymic epithelial cells, termed Nucleoprotein Receptor (NR), inducing growth arrest
  • 细胞定位
    Virion. Host cytoplasm.
  • 数据库链接
  • 别名
    • Measles nucleocapsid protein antibody
    • N antibody
    • NP antibody
    • Nucleocapsid protein antibody

文献

ab106292 has not yet been referenced specifically in any publications.

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