Anti-Measles nucleoprotein抗体[2F3] (ab106292)
Key features and details
- Mouse monoclonal [2F3] to Measles nucleoprotein
- Suitable for: ICC/IF, ICC, WB, ELISA
- Isotype: IgG1
概述
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产品名称
Anti-Measles nucleoprotein抗体[2F3]
参阅全部 Measles nucleoprotein 一抗 -
描述
小鼠单克隆抗体[2F3] to Measles nucleoprotein -
宿主
Mouse -
经测试应用
适用于: ICC/IF, ICC, WB, ELISAmore details -
种属反应性
与反应: Measles virus -
免疫原
Recombinant Nucleoprotein
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. -
存储溶液
Constituents: 1.21% Tris, 0.75% Glycine, 2% Sucrose -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
2F3 -
同种型
IgG1 -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab106292于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
ICC/IF |
Use at an assay dependent dilution.
|
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ICC |
1/100 - 1/500.
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|
WB |
1/200 - 1/1000. Predicted molecular weight: 58 kDa.
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|
ELISA |
1/2000 - 1/10000.
|
说明 |
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ICC/IF
Use at an assay dependent dilution. |
ICC
1/100 - 1/500. |
WB
1/200 - 1/1000. Predicted molecular weight: 58 kDa. |
ELISA
1/2000 - 1/10000. |
靶标
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相关性
Involved in the encapsidating of the genome in a ratio of 1 N per 6 ribonucleotides, resulting in the protection from nucleases. The nucleocapsid (NC) has an helical structure with either 12.35 or 11.64 N per turn, approximately 20nm in diameter, with a hollow central cavity approximately 5nm in diameter. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases. N is released in the blood following lysis of measles infected cells, it interacts then with human FCGR2B on immune cells, inducing apoptosis and blocking inflammatory immune response. Ntail binds to a protein on human thymic epithelial cells, termed Nucleoprotein Receptor (NR), inducing growth arrest -
细胞定位
Virion. Host cytoplasm. -
别名
- Measles nucleocapsid protein antibody
- N antibody
- NP antibody
- Nucleocapsid protein antibody
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab106292 被引用在 3 文献中.
- Zhou D et al. Establishment of an efficient reverse genetic system of Mumps virus S79 from cloned DNA. World J Pediatr 15:499-505 (2019). PubMed: 31456156
- Böröcz K et al. Development of a robust and standardized immunoserological assay for detection of anti-measles IgG antibodies in human sera. J Immunol Methods N/A:N/A (2018). PubMed: 30056035
- Wang Y et al. Enhancement of safety and immunogenicity of the Chinese Hu191 measles virus vaccine by alteration of the S-adenosylmethionine (SAM) binding site in the large polymerase protein. Virology 518:210-220 (2018). PubMed: 29525671