RabMAb

Anti-MDC抗体[EP1363Y] (ab76094)

概述

  • 产品名称Anti-MDC抗体[EP1363Y]
    参阅全部 MDC 一抗
  • 描述
    兔单克隆抗体[EP1363Y] to MDC
  • 经测试应用适用于: WBmore details
    不适用于: Flow Cyt,IHC-P or IP
  • 种属反应性

    预测可用于: Mouse
  • 免疫原

    A synthetic peptide corresponding to residues near the C terminus of mouse MDC.

  • 阳性对照
    • Mouse MDC recombinant protein.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

     

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Human, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 纯度Tissue culture supernatant
  • 克隆单克隆
  • 克隆编号EP1363Y
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab76094 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 8 kDa (predicted molecular weight: 10 kDa).
  • 应用说明Is unsuitable for Flow Cyt,IHC-P or IP.
  • 靶标

    • 功能May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.
    • 组织特异性Highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus. Also found in lymph node, appendix, activated monocytes, resting and activated macrophages. Lower expression in lung and spleen. Very weak expression in small intestine. In lymph node expressed in a mature subset of Langerhans' cells (CD1a+ and CD83+). Expressed in Langerhans' cell histiocytosis but not in dermatopathic lymphadenopathy. Expressed in atopic dermatitis, allergic contact dermatitis skin, and psoriasis, in both the epidermis and dermis.
    • 序列相似性Belongs to the intercrine beta (chemokine CC) family.
    • 翻译后修饰The N-terminal processed forms MDC(3-69), MDC(5-69) and MDC(7-69) are produced by proteolytic cleavage after secretion from monocyte derived dendrocytes.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • A 152E5.1 antibody
      • ABCD 1 antibody
      • ABCD1 antibody
      • C C motif chemokine 22 antibody
      • CC chemokine STCP 1 antibody
      • CC chemokine STCP-1 antibody
      • ccl 22 antibody
      • Ccl22 antibody
      • CCL22_HUMAN antibody
      • Chemokine (C C motif) ligand 22 antibody
      • DC/B CK antibody
      • DCBCK antibody
      • Macrophage-derived chemokine antibody
      • MDC antibody
      • MDC(1-69) antibody
      • MDC(7-69) antibody
      • MGC34554 antibody
      • SCYA22 antibody
      • Small inducible cytokine subfamily A (Cys Cys) member 22 antibody
      • Small inducible cytokine subfamily A, member 22 antibody
      • Small-inducible cytokine A22 antibody
      • STCP 1 antibody
      • STCP1 antibody
      • Stimulated T cell chemotactic protein 1 antibody
      • Stimulated T-cell chemotactic protein 1 antibody
      see all

    Anti-MDC antibody [EP1363Y] 图像

    • Anti-MDC antibody [EP1363Y] (ab76094) at 1/500 dilution + mouse MDC recombinant protein at 0.005 µg

      Secondary
      Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size : 10 kDa
      Observed band size : 8 kDa (why is the actual band size different from the predicted?)

    Anti-MDC antibody [EP1363Y] (ab76094)参考文献

    ab76094 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"