Anti-MDC抗体(Biotin) (ab83129)


  • 产品名称Anti-MDC抗体(Biotin)
    参阅全部 MDC 一抗
  • 描述
    兔多克隆抗体to MDC (Biotin)
  • 偶联物Biotin
  • 经测试应用适用于: WB, ELISA, Sandwich ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length Human MDC protein, highly pure (>98%).


  • 形式Lyophilised:Reconstitute in sterile PBS containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 纯度IgG fraction
  • 纯化说明ab83129 was purified by affinity chromatography and then biotinylated. Filter Sterilised.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域


Our Abpromise guarantee covers the use of ab83129 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 11 kDa.

Detection limit for recombinant hMDC is 1.5 - 3 ng/lane, under either reducing or non-reducing conditions.

ELISA Use a concentration of 0.25 - 1 µg/ml.

Can detect 0.2 - 0.4 ng/well of recombinant hMDC.

Sandwich ELISA Use a concentration of 0.25 - 1 µg/ml.

In sandwich ELISA, this antibody can be used as the detection antibody along with either ab9847 or ab9857 as the capture antibody to detec at least 0.2 - 0.4 ng/well of recombinant hMDC.


  • 功能May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.
  • 组织特异性Highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus. Also found in lymph node, appendix, activated monocytes, resting and activated macrophages. Lower expression in lung and spleen. Very weak expression in small intestine. In lymph node expressed in a mature subset of Langerhans' cells (CD1a+ and CD83+). Expressed in Langerhans' cell histiocytosis but not in dermatopathic lymphadenopathy. Expressed in atopic dermatitis, allergic contact dermatitis skin, and psoriasis, in both the epidermis and dermis.
  • 序列相似性Belongs to the intercrine beta (chemokine CC) family.
  • 翻译后修饰The N-terminal processed forms MDC(3-69), MDC(5-69) and MDC(7-69) are produced by proteolytic cleavage after secretion from monocyte derived dendrocytes.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • A 152E5.1 antibody
    • ABCD 1 antibody
    • ABCD1 antibody
    • C C motif chemokine 22 antibody
    • CC chemokine STCP 1 antibody
    • CC chemokine STCP-1 antibody
    • ccl 22 antibody
    • Ccl22 antibody
    • CCL22_HUMAN antibody
    • Chemokine (C C motif) ligand 22 antibody
    • DC/B CK antibody
    • DCBCK antibody
    • Macrophage-derived chemokine antibody
    • MDC(1-69) antibody
    • MDC(7-69) antibody
    • MGC34554 antibody
    • SCYA22 antibody
    • Small inducible cytokine subfamily A (Cys Cys) member 22 antibody
    • Small-inducible cytokine A22 antibody
    • STCP 1 antibody
    • STCP1 antibody
    • Stimulated T cell chemotactic protein 1 antibody
    • Stimulated T-cell chemotactic protein 1 antibody
    see all

Anti-MDC antibody (Biotin) (ab83129)参考文献

ab83129 has not yet been referenced specifically in any publications.

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