生物素Anti-MDC抗体(ab83129)
Key features and details
- Biotin Rabbit polyclonal to MDC
- Suitable for: WB, Sandwich ELISA
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG
概述
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产品名称
生物素Anti-MDC抗体
参阅全部 MDC 一抗 -
描述
生物素兔多克隆抗体to MDC -
宿主
Rabbit -
偶联物
Biotin -
经测试应用
适用于: WB, Sandwich ELISAmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length Human MDC protein, highly pure (>98%).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Lyophilized:Reconstitute in sterile PBS containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Constituent: PBS -
Concentration information loading...
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纯度
IgG fraction -
纯化说明
ab83129 was purified by affinity chromatography and then biotinylated. Filter Sterilised. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab83129于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 11 kDa.
Detection limit for recombinant hMDC is 1.5 - 3 ng/lane, under either reducing or non-reducing conditions. |
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Sandwich ELISA |
说明 |
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WB
Use at an assay dependent concentration. Predicted molecular weight: 11 kDa. Detection limit for recombinant hMDC is 1.5 - 3 ng/lane, under either reducing or non-reducing conditions. |
靶标
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功能
May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active. -
组织特异性
Highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus. Also found in lymph node, appendix, activated monocytes, resting and activated macrophages. Lower expression in lung and spleen. Very weak expression in small intestine. In lymph node expressed in a mature subset of Langerhans' cells (CD1a+ and CD83+). Expressed in Langerhans' cell histiocytosis but not in dermatopathic lymphadenopathy. Expressed in atopic dermatitis, allergic contact dermatitis skin, and psoriasis, in both the epidermis and dermis. -
序列相似性
Belongs to the intercrine beta (chemokine CC) family. -
翻译后修饰
The N-terminal processed forms MDC(3-69), MDC(5-69) and MDC(7-69) are produced by proteolytic cleavage after secretion from monocyte derived dendrocytes. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 6367 Human
- Omim: 602957 Human
- SwissProt: O00626 Human
- Unigene: 534347 Human
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别名
- A 152E5.1 antibody
- ABCD 1 antibody
- ABCD1 antibody
see all
数据表及文件
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Datasheet download
文献 (0)
ab83129 尚未被引用在任何文献中。