概述

  • 产品名称Anti-MD2抗体[4H1]
    参阅全部 MD2 一抗
  • 描述
    小鼠单克隆抗体[4H1] to MD2
  • 特异性Reacts with both the monomeric and polymeric forms of soluble Human MD2 and the MD2/Toll-like receptor 4 complex. Able to inhibit LPS binding to MD2. It does not cross-react with Mouse MD2.
  • 经测试应用适用于: WB, ELISA, Functional Studies, ICC/IFmore details
  • 种属反应性
    与反应: Human
    不与反应: Mouse
  • 免疫原

    Baculovirally expressed His tagged Human MD2.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 0.1% BSA, PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明ab106132 was 0.2 µm filtered prior to formulation.
  • 克隆单克隆
  • 克隆编号4H1
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab106132 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50. Predicted molecular weight: 19 kDa.
ELISA 1/50.
Functional Studies Use at an assay dependent dilution.
ICC/IF 1/50.

靶标

  • 功能Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS.
  • 翻译后修饰N-glycosylated; high-mannose.
  • 细胞定位Secreted > extracellular space.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ESOP 1 antibody
    • ESOP-1 antibody
    • ESOP1 antibody
    • LY 96 antibody
    • Ly-96 antibody
    • LY96 antibody
    • LY96_HUMAN antibody
    • Lymphocyte antigen 96 antibody
    • md 2 antibody
    • MD 2 protein antibody
    • MD2 protein antibody
    • Myeloid differentiation protein 2 antibody
    • Protein MD 2 antibody
    • Protein MD-2 antibody
    • Protein MD2 antibody
    see all

Anti-MD2 antibody [4H1] (ab106132)参考文献

ab106132 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"