Anti-MD2抗体[18H10] (FITC) (ab106105)

概述

  • 产品名称Anti-MD2抗体[18H10] (FITC)
    参阅全部 MD2 一抗
  • 描述
    小鼠单克隆抗体[18H10] to MD2 (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 特异性ab106105 reacts with MD2. However, it does not react with sMD2.
  • 经测试应用适用于: Functional Studies, Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    TLR4/MD2 expressing CHO cells/ chimeric TLR4/MD2 fusion protein

  • 常规说明


    The monoclonal antibody 18H10 is able to inhibit bacterial binding to MD2.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: None
    Constituents: 1% BSA, PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • Primary antibody说明The monoclonal antibody 18H10 is able to inhibit bacterial binding to MD2.
  • 克隆单克隆
  • 克隆编号18H10
  • 同种型IgG2b
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab106105 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Functional Studies Use at an assay dependent concentration.
Flow Cyt 1/50. ab91368-Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS.
  • 翻译后修饰N-glycosylated; high-mannose.
  • 细胞定位Secreted > extracellular space.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ESOP 1 antibody
    • ESOP-1 antibody
    • ESOP1 antibody
    • LY 96 antibody
    • Ly-96 antibody
    • LY96 antibody
    • LY96_HUMAN antibody
    • Lymphocyte antigen 96 antibody
    • md 2 antibody
    • MD 2 protein antibody
    • MD2 protein antibody
    • Myeloid differentiation protein 2 antibody
    • Protein MD 2 antibody
    • Protein MD-2 antibody
    • Protein MD2 antibody
    see all

Anti-MD2 antibody [18H10] (FITC) (ab106105)参考文献

ab106105 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry.

This antibody to MD-2, clone 18H10, has been extensively published. For flow cytometry data please refer to the 4 publications below.


1. Pugin, J et al; Soluble MD-2 activity in plasma from patient...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"