The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/400. Predicted molecular weight: 52 kDa.
功能Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a high affinity pyruvate transporter.
组织特异性High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and Leukocyte. Restricted expression in normal tissues, but widely expressed in cancer cells.
序列相似性Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.