RabMAb

Anti-MCRS1抗体[EPR5855] (ab124704)

概述

  • 产品名称Anti-MCRS1抗体[EPR5855]
    参阅全部 MCRS1 一抗
  • 描述
    兔单克隆抗体[EPR5855] to MCRS1
  • 经测试应用适用于: WB, IPmore details
    不适用于: Flow Cyt,ICC or IHC-P
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A synthetic peptide corresponding to residues in Human MCRS1.

  • 阳性对照
    • HeLa, HCT 116, Jurkat and LnCaP cell lysates.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

性能

应用

Our Abpromise guarantee covers the use of ab124704 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/10000 - 1/50000. Detects a band of approximately 52 kDa (predicted molecular weight: 52 kDa).
IP 1/10 - 1/100.
  • 应用说明Is unsuitable for Flow Cyt,ICC or IHC-P.
  • 靶标

    • 功能Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. May be an inhibitor of TERT telomerase activity.
      Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
    • 组织特异性Detected in testis, and at lower levels in spleen, thymus, prostate, uterus, small intestine, colon and leukocytes.
    • 序列相似性Contains 1 FHA domain.
    • 发展阶段Cell-cycle regulated: levels are highest early in S phase; not detectable in G2.
    • 细胞定位Nucleus. Nucleus > nucleolus. In microspherules in the nucleolus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 58 kDa microspherule protein antibody
      • Cell cycle regulated factor (78 kDa) antibody
      • Cell cycle regulated factor p78 antibody
      • Cell cycle-regulated factor p78 antibody
      • ICP22BP antibody
      • INO80 complex subunit J antibody
      • MCRS 1 antibody
      • MCRS 2 antibody
      • MCRS1 antibody
      • MCRS1_HUMAN antibody
      • MCRS2 antibody
      • Microspherule protein 1 antibody
      • MSP 58 antibody
      • MSP58 antibody
      • p78 antibody
      see all

    Anti-MCRS1 antibody [EPR5855] 图像

    • All lanes : Anti-MCRS1 antibody [EPR5855] (ab124704) at 1/10000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : HCT 116 cell lysate
      Lane 3 : Jurkat cell lysate
      Lane 4 : LnCaP cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      Goat anti-Rabbit HRP at 1/2000 dilution

      Predicted band size : 52 kDa
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    Anti-MCRS1 antibody [EPR5855] (ab124704)参考文献

    ab124704 has not yet been referenced specifically in any publications.

    Product Wall

    Application Western blot
    Loading amount 10 µg
    Gel Running Conditions Reduced Denaturing
    Sample Human Cell lysate - whole cell (colon)
    Specification colon
    Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
    Username

    Dr. Chiara Vardabasso

    Verified customer

    提交于 Nov 26 2014

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"